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No matches for "

68818

" within the MedChemExpress (MCE) catalog. Here are the results you might be looking for.

30

Inhibitors & Agonists

1

Peptides

5

Antibodies

24

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-15652
    Freselestat

    ONO-6818; ONO-PO-736

    		 Elastase Inflammation/Immunology
    Freselestat (ONO-6818) is a potent and orally active neutrophil elastase inhibitor with a Ki of 12.2 nM. Freselestat is >100-fold less-active against other proteases such as trypsin, protein-ase 3, pancreatic elastase, plasmin, thrombin, collagenase, cathepsin G, and murine macrophage elastase. Freselestat has a potent anti-inflammatory activity .
    Freselestat
  • HY-125693
    L685818

    		Fungal Infection Neurological Disease
    L685818 is a specific immunophilin ligand. L685818 was neuroregenerative and non-neuroprotective in primary brain cultures. L685818 protects dopaminergic neurons from toxic inhibition of MPP+ and 6-OHDA, reduces tyrosine hydroxylase (TH) loss, and promotes neuronal process regeneration. L685818 is also an antifungal reagent for Cryptococcus neoformans .
    L685818
  • HY-15652A
    Freselestat quarterhydrate

    ONO-6818 quarterhydrate; ONO-PO-736 quarterhydrate

    		 Elastase Inflammation/Immunology
    Freselestat quarterhydrate (ONO-6818 quarterhydrate) is a potent and orally active neutrophil elastase inhibitor with a Ki of 12.2 nM. Freselestat quarterhydrate is >100-fold less-active against other proteases such as trypsin, protein-ase 3, pancreatic elastase, plasmin, thrombin, collagenase, cathepsin G, and murine macrophage elastase. Freselestat quarterhydrate has a potent anti-inflammatory activity .
    Freselestat quarterhydrate
  • HY-19156A
    ZD-6888 hydrochloride

    ICI-D 6888 hydrochloride

    		 Angiotensin Receptor Others
    ZD-6888 hydrochloride (ICI-D 6888 hydrochloride) is an antagonist for angiotensin II, which competitively inhibits the angiotensin II-mediated release of renin, affects the renal structure and function .
    ZD-6888 hydrochloride
  • HY-19156
    ZD-6888

    ICI-D 6888

    		 Drug Derivative Others
    ZD-6888 is an active compound.
    ZD-6888
  • HY-R02337A
    hsa-miR-6888-5p agomir

    		MicroRNA Cancer
    hsa-miR-6888-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    hsa-miR-6888-5p agomir
    hsa-miR-6888-5p agomir
  • HY-R02322
    hsa-miR-6881-3p mimic

    		MicroRNA Cancer
    hsa-miR-6881-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
    hsa-miR-6881-3p mimic
    hsa-miR-6881-3p mimic
  • HY-R02200
    hsa-miR-6818-3p mimic

    		MicroRNA Cancer
    hsa-miR-6818-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
    hsa-miR-6818-3p mimic
    hsa-miR-6818-3p mimic
  • HY-R02323
    hsa-miR-6881-5p mimic

    		MicroRNA Cancer
    hsa-miR-6881-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
    hsa-miR-6881-5p mimic
    hsa-miR-6881-5p mimic
  • HY-RI02336A
    hsa-miR-6888-3p antagomir

    		MicroRNA Cancer
    hsa-miR-6888-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    hsa-miR-6888-3p antagomir
    hsa-miR-6888-3p antagomir
  • HY-R02336
    hsa-miR-6888-3p mimic

    		MicroRNA Cancer
    hsa-miR-6888-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
    hsa-miR-6888-3p mimic
    hsa-miR-6888-3p mimic
  • HY-R02201
    hsa-miR-6818-5p mimic

    		MicroRNA Cancer
    hsa-miR-6818-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
    hsa-miR-6818-5p mimic
    hsa-miR-6818-5p mimic
  • HY-RI02323A
    hsa-miR-6881-5p antagomir

    		MicroRNA Cancer
    hsa-miR-6881-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    hsa-miR-6881-5p antagomir
    hsa-miR-6881-5p antagomir
  • HY-P11210
    A68828

    		Biochemical Assay Reagents Inflammation/Immunology
    A68828 is an atrial natriuretic factor (ANF) analog. A68828 can improve renal function in an acute model of postischemic acute renal failure. A68828 can be studied in research on ischemic acute renal failure .
    A68828
  • HY-RI02322
    hsa-miR-6881-3p inhibitor

    		MicroRNA Cancer
    hsa-miR-6881-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
    hsa-miR-6881-3p inhibitor
    hsa-miR-6881-3p inhibitor
  • HY-R02322A
    hsa-miR-6881-3p agomir

    		MicroRNA Cancer
    hsa-miR-6881-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    hsa-miR-6881-3p agomir
    hsa-miR-6881-3p agomir
  • HY-RI02201
    hsa-miR-6818-5p inhibitor

    		MicroRNA Cancer
    hsa-miR-6818-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
    hsa-miR-6818-5p inhibitor
    hsa-miR-6818-5p inhibitor
  • HY-RI02200A
    hsa-miR-6818-3p antagomir

    		MicroRNA Cancer
    hsa-miR-6818-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    hsa-miR-6818-3p antagomir
    hsa-miR-6818-3p antagomir
  • HY-R02323A
    hsa-miR-6881-5p agomir

    		MicroRNA Cancer
    hsa-miR-6881-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    hsa-miR-6881-5p agomir
    hsa-miR-6881-5p agomir
  • HY-RI02201A
    hsa-miR-6818-5p antagomir

    		MicroRNA Cancer
    hsa-miR-6818-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    hsa-miR-6818-5p antagomir
    hsa-miR-6818-5p antagomir
  • HY-R02336A
    hsa-miR-6888-3p agomir

    		MicroRNA Cancer
    hsa-miR-6888-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    hsa-miR-6888-3p agomir
    hsa-miR-6888-3p agomir
  • HY-RI02323
    hsa-miR-6881-5p inhibitor

    		MicroRNA Cancer
    hsa-miR-6881-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
    hsa-miR-6881-5p inhibitor
    hsa-miR-6881-5p inhibitor
  • HY-RI02322A
    hsa-miR-6881-3p antagomir

    		MicroRNA Cancer
    hsa-miR-6881-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    hsa-miR-6881-3p antagomir
    hsa-miR-6881-3p antagomir
  • HY-R02200A
    hsa-miR-6818-3p agomir

    		MicroRNA Cancer
    hsa-miR-6818-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    hsa-miR-6818-3p agomir
    hsa-miR-6818-3p agomir
  • HY-R02201A
    hsa-miR-6818-5p agomir

    		MicroRNA Cancer
    hsa-miR-6818-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    hsa-miR-6818-5p agomir
    hsa-miR-6818-5p agomir
  • HY-RI02337
    hsa-miR-6888-5p inhibitor

    		MicroRNA Cancer
    hsa-miR-6888-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
    hsa-miR-6888-5p inhibitor
    hsa-miR-6888-5p inhibitor
  • HY-RI02336
    hsa-miR-6888-3p inhibitor

    		MicroRNA Cancer
    hsa-miR-6888-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
    hsa-miR-6888-3p inhibitor
    hsa-miR-6888-3p inhibitor
  • HY-RI02200
    hsa-miR-6818-3p inhibitor

    		MicroRNA Cancer
    hsa-miR-6818-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
    hsa-miR-6818-3p inhibitor
    hsa-miR-6818-3p inhibitor
  • HY-R02337
    hsa-miR-6888-5p mimic

    		MicroRNA Cancer
    hsa-miR-6888-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
    hsa-miR-6888-5p mimic
    hsa-miR-6888-5p mimic
  • HY-RI02337A
    hsa-miR-6888-5p antagomir

    		MicroRNA Cancer
    hsa-miR-6888-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    hsa-miR-6888-5p antagomir
    hsa-miR-6888-5p antagomir

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