2. Gene
  3. Sik3 - SIK family kinase 3 Gene

Sik3 - SIK family kinase 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Qsk; SIK-3; mKIAA0999; 5730525O22Rik; 9030204A07Rik

Gene ID: 70661 | Gene type: protein coding

About Sik3

Chromosome 9: 45,924,118-46,135,492 forward strand.GRCm39:CM001002.3

This gene has 7 transcripts (splice variants), 224 orthologues, 19 paralogues and is associated with 223 phenotypes. Ubiquitous expression in cerebellum adult (RPKM 12.2), adrenal adult (RPKM 1.1) and 28 other tissues.

Summary

Predicted to enable ATP binding activity; magnesium ion binding activity; and protein kinase activity. Acts upstream of or within endochondral bone morphogenesis; limb morphogenesis; and regulation of protein localization. Located in cytoplasm. Is expressed in Meckel's cartilage and vibrissa. Orthologous to human SIK3 (SIK family kinase 3). [provided by Alliance of Genome Resources, Apr 2022]

Sik3 Products(1)

mRNA Protein Name
NM_027498.3 NP_081774.3 serine/threonine-protein kinase SIK3

Sik3 Protein Structure

STKc_SIK

STKc_SIK: cd14071 (64 - 316)

UBA_SIK3

UBA_SIK3: cd14410 (345 - 389)

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  • 1369 a.a.
Protein Preferred Names Protein Names

serine/threonine-protein kinase SIK3

salt-inducible kinase 3

serine/threonine-protein kinase QSK

Related Agents

Pre-clinical Phase
Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-101147 YKL-05-099 Inhibitor 99.76% Unkown
HY-120856 ARN-3236 Inhibitor 98.60% Unkown
HY-120877 MRT199665 Inhibitor 99.92% Unkown
HY-139253 MRIA9 Inhibitor 98.34% Unkown
HY-157442 GLPG3312 Inhibitor 98.25% Unkown
HY-148061 DB1113 99.28% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sik3 NCBI NCBI:23387