Chmp4b - charged multivesicular body protein 4B Gene

Also Known as Snf7-2; 2010012F05Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 75608

Summary

Predicted to enable protein homodimerization activity. Involved in regulation of Autophagy. Located in cytosol; membrane; and nucleus. Is expressed in several structures, including brain; genitourinary system; liver; lung; and spleen. Human ortholog(s) of this gene implicated in cataract 31 multiple types. Orthologous to human CHMP4B (charged multivesicular body protein 4B). [provided by Alliance of Genome Resources, Apr 2022]

Chmp4b Products (1)

mRNA Protein Name
NM_029362.4 NP_083638.1 charged multivesicular body protein 4b

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
17683935 MGI
Biological Process GO Annotation Evidence References Source
involved in regulation of autophagy IMP
IMP: Inferred from mutant phenotype
17683935 MGI
Cellular Component GO Annotation Evidence References Source
located in cytosol IDA
IDA: Inferred from direct assay
17683935 MGI
located in endosome membrane IDA
IDA: Inferred from direct assay
26720614 MGI
located in membrane IDA
IDA: Inferred from direct assay
17683935 MGI
located in nucleus IDA
IDA: Inferred from direct assay
17683935 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

charged multivesicular body protein 4b

  • chromatin modifying protein 4B

  • chromatin-modifying protein 4b

Chmp4b Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Cross
Chmp4b Q9D8B3 PDCD6IP Homo sapiens Q8WUM4
Anti Tag CoIP
26496610
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02643 CHMP4A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS02644 CHMP4B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21837 Chmp4b Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Chmp4b NCBI NCBI:128866