ZNF16 - zinc finger protein 16 Gene

Also Known as HZF1; KOX9

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 7564

Summary

The protein encoded by this gene contains multiple tandem zinc finger motifs. The encoded protein is involved in the differentiation of erythroid and megakaryocytic cells. This gene is located in a cluster of related genes on chromosome 8 encoding zinc finger proteins. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2012]
Ubiquitous expression in ovary (RPKM 5.1), testis (RPKM 4.3) and 25 other tissues.

ZNF16 Products (6)

mRNA Protein Name
NM_001029976.3 NP_001025147.2 zinc finger protein 16 isoform 1
NM_001413564.1 NP_001400493.1 zinc finger protein 16 isoform 1
NM_001413565.1 NP_001400494.1 zinc finger protein 16 isoform 1
NM_001413566.1 NP_001400495.1 zinc finger protein 16 isoform 1
NM_001413567.1 NP_001400496.1 zinc finger protein 16 isoform 2
NM_006958.3 NP_008889.2 zinc finger protein 16 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
21874239 GOA
Biological Process GO Annotation Evidence References Source
involved in cellular response to sodium dodecyl sulfate IDA
IDA: Inferred from direct assay
21874239 GOA
involved in negative regulation of apoptotic process IDA
IDA: Inferred from direct assay
21874239 GOA
involved in positive regulation of cell cycle phase transition IDA
IDA: Inferred from direct assay
21874239 GOA
involved in positive regulation of cell population proliferation IDA
IDA: Inferred from direct assay
21874239 GOA
involved in positive regulation of erythrocyte differentiation IMP
IMP: Inferred from mutant phenotype
16628192 GOA
involved in positive regulation of kinase activity IDA
IDA: Inferred from direct assay
21874239 GOA
involved in positive regulation of megakaryocyte differentiation IMP
IMP: Inferred from mutant phenotype
16628192 GOA
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
16628192 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZNF16 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
ZNF16 P17020 FAIM Homo sapiens Q9NVQ4-2
Validated Y2H
32296183
Intra
ZNF16 P17020 ZNF101 Homo sapiens Q8IZC7
Y2H Prey Pooling
25416956
Intra
ZNF16 P17020 ZNF101 Homo sapiens Q8IZC7
Y2H Array
25416956
Intra
ZNF16 P17020 AQP1 Homo sapiens P29972
Validated Y2H
32296183
Intra
ZNF16 P17020 ZCCHC17 Homo sapiens Q9NP64
Validated Y2H
32296183
Intra
ZNF16 P17020 ZBTB47 Homo sapiens Q9UFB7
Validated Y2H
32296183
Intra
ZNF16 P17020 ZBTB47 Homo sapiens Q9UFB7
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS16106 ZNF165 Human Pre-designed siRNA Set A Pre-designed Set / Unkown