ZCCHC17 - zinc finger CCHC-type containing 17 Gene

Also Known as PS1D; pNO40; HSPC251

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 51538

About ZCCHC17

Cytogenetic location: 1p35.2 Genomic coordinates (GRCh38): 1:31,297,032-31,364,936 (from NCBI)

This gene has 9 transcripts (splice variants) and 205 orthologues. Ubiquitous expression in heart (RPKM 23.1), brain (RPKM 18.8) and 24 other tissues.

Summary

Enables identical protein binding activity. Predicted to be involved in RNA stabilization. Predicted to be located in nucleolus. Predicted to be part of cytosolic large ribosomal subunit. [provided by Alliance of Genome Resources, Apr 2022]

ZCCHC17 Products (10)

mRNA Protein Name
NM_001282566.2 NP_001269495.1 zinc finger CCHC domain-containing protein 17 isoform a
NM_001282567.2 NP_001269496.1 zinc finger CCHC domain-containing protein 17 isoform b
NM_001282568.2 NP_001269497.1 zinc finger CCHC domain-containing protein 17 isoform c
NM_001282569.2 NP_001269498.1 zinc finger CCHC domain-containing protein 17 isoform d
NM_001282570.2 NP_001269499.1 zinc finger CCHC domain-containing protein 17 isoform e
NM_001282571.2 NP_001269500.1 zinc finger CCHC domain-containing protein 17 isoform f
NM_001282572.2 NP_001269501.1 zinc finger CCHC domain-containing protein 17 isoform g
NM_001282573.2 NP_001269502.1 zinc finger CCHC domain-containing protein 17 isoform h
NM_001282574.2 NP_001269503.1 zinc finger CCHC domain-containing protein 17 isoform i
NM_016505.4 NP_057589.2 zinc finger CCHC domain-containing protein 17 isoform c

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
16189514 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZCCHC17 Protein Structure

S1

S1: S1 RNA binding domain (17 - 85)

  • 0
  • 100
  • 200
  • 241 a.a.
Protein Preferred Names Protein Names

zinc finger CCHC domain-containing protein 17

nucleolar protein of 40 kDa

  • nucleolar protein 40

ZCCHC17 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
ZCCHC17 Q9NP64 RNF4 Homo sapiens P78317
Y2H Prey Pooling
32296183
Intra
ZCCHC17 Q9NP64 RNF4 Homo sapiens P78317
Y2H Array
32296183
Intra
ZCCHC17 Q9NP64 q9y649_human Homo sapiens Q9Y649
Y2H Array
32814053
Intra
ZCCHC17 Q9NP64 q9y649_human Homo sapiens Q9Y649
Y2H Pooling
32814053
Intra
ZCCHC17 Q9NP64 q9y649_human Homo sapiens Q9Y649
Validated Y2H
32814053
Intra
ZCCHC17 Q9NP64 FGFR3 Homo sapiens P22607
Y2H Pooling
32814053
Intra
ZCCHC17 Q9NP64 FGFR3 Homo sapiens P22607
Validated Y2H
32814053
Intra
ZCCHC17 Q9NP64 FGFR3 Homo sapiens P22607
Y2H Array
32814053
Intra
ZCCHC17 Q9NP64 GSN Homo sapiens P06396
Validated Y2H
32814053
Intra
ZCCHC17 Q9NP64 GSN Homo sapiens P06396
Y2H Array
32814053
Intra
ZCCHC17 Q9NP64 GSN Homo sapiens P06396
Y2H Pooling
32814053
Intra
ZCCHC17 Q9NP64 ZNF16 Homo sapiens P17020
Y2H Array
32296183
Intra
ZCCHC17 Q9NP64 ZNF16 Homo sapiens P17020
Y2H Prey Pooling
32296183
Intra
ZCCHC17 Q9NP64 SDCBP Homo sapiens O00560
Y2H Prey Pooling
32296183
Intra
ZCCHC17 Q9NP64 SDCBP Homo sapiens O00560
Y2H Array
32296183
Intra
ZCCHC17 Q9NP64 SDCBP Homo sapiens O00560
Y2H Prey Pooling
25416956
Intra
ZCCHC17 Q9NP64 SDCBP2 Homo sapiens Q9H190
Y2H Prey Pooling
32296183
Intra
ZCCHC17 Q9NP64 SDCBP2 Homo sapiens Q9H190
Y2H Array
25416956
Intra
ZCCHC17 Q9NP64 SDCBP2 Homo sapiens Q9H190
Y2H Array
32296183
Intra
ZCCHC17 Q9NP64 SDCBP2 Homo sapiens Q9H190
Y2H
21516116
Intra
ZCCHC17 Q9NP64 JMJD6 Homo sapiens Q6NYC1
Anti Tag CoIP
23455924
Intra
ZCCHC17 Q9NP64 JMJD6 Homo sapiens Q6NYC1
Anti Tag CoIP
33961781
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS16002 ZCCHC17 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta ZCCHC17 VGNC VGNC:79840
Mus musculus ZCCHC17 MGD MGI:1919955
Felis catus ZCCHC17 VGNC VGNC:80409
Rattus norvegicus ZCCHC17 RGD RGD:1565267
Others ZCCHC17 NCBI