ZBTB35 - zinc finger and BTB domain containing 35 Gene

Also Known as ZNF131; pHZ-10

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 7690

Summary

Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II; regulation of cytokine production; and regulation of immune system process. Located in intermediate filament Cytoskeleton and nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025]
Ubiquitous expression in testis (RPKM 10.2), bone marrow (RPKM 5.2) and 25 other tissues.

ZBTB35 Products (17)

mRNA Protein Name
NM_001297548.3 NP_001284477.1 zinc finger protein 131 isoform 1
NM_001330704.2 NP_001317633.1 zinc finger protein 131 isoform 3
NM_001330705.1 NP_001317634.1 zinc finger protein 131 isoform 3
NM_001330706.2 NP_001317635.1 zinc finger protein 131 isoform 2
NM_001330707.2 NP_001317636.1 zinc finger protein 131 isoform 1
NM_001330708.2 NP_001317637.1 zinc finger protein 131 isoform 1
NM_001330709.2 NP_001317638.1 zinc finger protein 131 isoform 3
NM_001330710.2 NP_001317639.1 zinc finger protein 131 isoform 3
NM_001330711.2 NP_001317640.1 zinc finger protein 131 isoform 2
NM_001330712.2 NP_001317641.1 zinc finger protein 131 isoform 1
NM_001330713.2 NP_001317642.1 zinc finger protein 131 isoform 2
NM_001330714.2 NP_001317643.1 zinc finger protein 131 isoform 1
NM_001330715.2 NP_001317644.1 zinc finger protein 131 isoform 2
NM_001330716.2 NP_001317645.1 zinc finger protein 131 isoform 4
NM_001330717.2 NP_001317646.1 zinc finger protein 131 isoform 5
NM_001388319.1 NP_001375248.1 zinc finger protein 131 isoform 2
NM_003432.4 NP_003423.1 zinc finger protein 131 isoform 2

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZBTB35 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
ZNF131 P52739 FHL2 Homo sapiens Q14192
Y2H Array
31515488
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15972 ZBTB33 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15970 ZBTB3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15971 ZBTB32 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15973 ZBTB38 Human Pre-designed siRNA Set A Pre-designed Set / Unkown