Sla2 - Src-like-adaptor 2 Gene

Also Known as SLAP2; SLAP-2; A930009E21Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 77799

Summary

Predicted to enable 1-phosphatidylinositol-3-kinase regulator activity; protein N-terminus binding activity; and signaling adaptor activity. Acts upstream of or within T cell activation. Located in late endosome and plasma membrane. Is expressed in thymus primordium. Orthologous to human SLA2 (Src like adaptor 2). [provided by Alliance of Genome Resources, Apr 2022]

Sla2 Products (2)

mRNA Protein Name
NM_001356495.1 NP_001343424.1 src-like-adapter 2
NM_029983.6 NP_084259.1 src-like-adapter 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
11891219 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within T cell activation IDA
IDA: Inferred from direct assay
11891219 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasmic vesicle IDA
IDA: Inferred from direct assay
12024036 MGI
located in late endosome IDA
IDA: Inferred from direct assay
12024036 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
12024036 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

src-like-adapter 2

  • modulator of antigen receptor signaling MARS

  • src-like adapter protein 2

Sla2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Cross
Sla2 Q8R4L0 FLT3 Homo sapiens P36888
Pull Down
27458164
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12976 SLA2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sla2 NCBI NCBI:84174