2. Gene
  3. DSCC1 - DNA replication and sister chromatid cohesion 1 Gene

DSCC1 - DNA replication and sister chromatid cohesion 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as DCC1

Gene ID: 79075 | Gene type: protein coding

About DSCC1

Cytogenetic location: 8q24.12 Genomic coordinates (GRCh38): 8:119,833,976-119,855,894 (from NCBI)

This gene has 2 transcripts (splice variants) and 204 orthologues. Ubiquitous expression in lymph node (RPKM 3.7), appendix (RPKM 2.3) and 24 other tissues.

Summary

CHTF18 (MIM 613201), CHTF8 (MIM 613202), and DSCC1 are components of an alternative replication factor C (RFC) (see MIM 600404) complex that loads PCNA (MIM 176740) onto DNA during S phase of the cell cycle (Merkle et al., 2003 [PubMed 12766176]; Bermudez et al., 2003 [PubMed 12930902]).[supplied by OMIM, Dec 2009]

DSCC1 Products(1)

mRNA Protein Name
NM_024094.3 NP_076999.2 sister chromatid cohesion protein DCC1

DSCC1 Protein Structure

Dcc1

Dcc1: Sister chromatid cohesion protein Dcc1 (42 - 358)

  • 0
  • 100
  • 200
  • 300
  • 393 a.a.
Protein Preferred Names Protein Names

sister chromatid cohesion protein DCC1

defective in sister chromatid cohesion 1 homolog

Related Diseases

Diseases Alias
Amelogenesis Imperfecta, Hypomaturation Type, Iia3

Amelogenesis Imperfecta Hypomaturation Type 2a3

AI2A3

Amelogenesis Imperfecta Hypomaturation Type Iia3

Amelogenesis Imperfecta, Type Iia3

Amelogenesis Imperfecta Type Iia3

Amelogenesis Imperfecta, Hypomaturation Type, 2a3
Cornelia De Lange Syndrome

De Lange Syndrome

Brachmann De Lange Syndrome

Brachmann-De Lange Syndrome

Cdls

Bdls

Typus Degenerativus Amstelodamensis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04019 DSCC1 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris DSCC1 VGNC VGNC:51769
Mus musculus DSCC1 MGD MGI:1919357
Bos taurus DSCC1 VGNC VGNC:28217
Felis catus DSCC1 VGNC VGNC:61636
Macaca mulatta DSCC1 VGNC VGNC:71894
Rattus norvegicus DSCC1 RGD RGD:1561749