RTL10 - retrotransposon Gag like 10 Gene

Also Known as BOP; C22orf29

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 79680

About RTL10

This gene has 5 transcripts (splice variants), 14 orthologues and 10 paralogues. Ubiquitous expression in skin (RPKM 6.6), brain (RPKM 5.5) and 25 other tissues.

Summary

Involved in mitochondrial outer membrane permeabilization and regulation of mitochondrial membrane potential. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]

RTL10 Products (1)

mRNA Protein Name
NM_024627.6 NP_078903.3 protein Bop

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
23055042 GOA
Biological Process GO Annotation Evidence References Source
involved in mitochondrial outer membrane permeabilization IMP
IMP: Inferred from mutant phenotype
23055042 GOA
involved in regulation of mitochondrial membrane potential IMP
IMP: Inferred from mutant phenotype
23055042 GOA
Cellular Component GO Annotation Evidence References Source
located in mitochondrion IDA
IDA: Inferred from direct assay
23055042 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein Bop

  • BH3-only protein

RTL10 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
RTL10 Q7L3V2 MCL1 Homo sapiens Q07820
Anti Tag CoIP
23055042
Intra
RTL10 Q7L3V2 BCL2L1 Homo sapiens Q07817-1
Anti Tag CoIP
23055042
Intra
RTL10 Q7L3V2 GPRASP2 Homo sapiens Q96D09
BFG-2H
27107012
Intra
RTL10 Q7L3V2 BAX Homo sapiens Q07812
Anti Tag CoIP
23055042
Intra
RTL10 Q7L3V2 BAK1 Homo sapiens Q16611
Anti Tag CoIP
23055042
Intra
RTL10 Q7L3V2 BCL2L2 Homo sapiens Q92843
Anti Tag CoIP
23055042
Intra
RTL10 Q7L3V2 BCL2L2 Homo sapiens Q92843
Anti Bait CoIP
23055042
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12323 RTL10 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus RTL10 MGD MGI:3833934
Others RTL10 NCBI