PRKRIP1 - PRKR interacting protein 1 Gene

Also Known as C114; KRBOX3

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 79706

About PRKRIP1

Cytogenetic location: 7q22.1 Genomic coordinates (GRCh38): 7:102,396,363-102,426,666 (from NCBI)

This gene has 8 transcripts (splice variants) and 197 orthologues. Ubiquitous expression in testis (RPKM 12.5), lymph node (RPKM 10.7) and 25 other tissues.

Summary

Predicted to enable double-stranded RNA binding activity; protein kinase binding activity; and protein kinase inhibitor activity. Involved in renal system process. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

PRKRIP1 Products (1)

mRNA Protein Name
NM_024653.4 NP_078929.1 PRKR-interacting protein 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
Biological Process GO Annotation Evidence References Source
involved in renal system process IDA
IDA: Inferred from direct assay
21183621 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PRKRIP1 Protein Structure

DUF1168

DUF1168: Protein of unknown function (DUF1168) (42 - 176)

  • 0
  • 100
  • 184 a.a.
Protein Preferred Names Protein Names

PRKR-interacting protein 1

  • KRAB box domain containing 3

PRKRIP1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
PRKRIP1 Q9H875 TRAF2 Homo sapiens Q12933
Y2H Prey Pooling
25416956
Intra
PRKRIP1 Q9H875 CEP70 Homo sapiens Q8NHQ1
Y2H Prey Pooling
25416956
Intra
PRKRIP1 Q9H875 CEP70 Homo sapiens Q8NHQ1
Validated Y2H
25416956
Intra
PRKRIP1 Q9H875 CEP70 Homo sapiens Q8NHQ1
Y2H Array
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Fructose-1,6-Bisphosphatase Deficiency

  • Fructose-1,6-Diphosphatase Deficiency

  • Baker-Winegrad Disease

  • FBP1D

  • Fbpase Deficiency

  • Fructose 1,6 Diphosphatase Deficiency

  • Fructose 1 Phosphate Aldolase Deficiency

  • Fbp1 Deficiency

  • Hereditary Fructose Intolerance Syndrome
Noonan Syndrome 6

  • NS6

  • Noonan Syndrome, Type 6
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11158 PRKRIP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus PRKRIP1 RGD RGD:1595708
Felis catus PRKRIP1 VGNC VGNC:64357
Mus musculus PRKRIP1 MGD MGI:1914051
Bos taurus PRKRIP1 VGNC VGNC:49564
Canis familiaris PRKRIP1 VGNC VGNC:49780
Others PRKRIP1 NCBI