NOL9 - nucleolar protein 9 Gene

Also Known as Grc3; NET6

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 79707

About NOL9

This gene has 5 transcripts (splice variants), 196 orthologues and 1 paralogue. Ubiquitous expression in spleen (RPKM 3.0), bone marrow (RPKM 2.3) and 25 other tissues.

Summary

Enables polynucleotide 5'-hydroxyl-kinase activity. Involved in maturation of 5.8S rRNA. Located in intermediate filament Cytoskeleton and nucleolus. [provided by Alliance of Genome Resources, Apr 2022]

NOL9 Products (1)

mRNA Protein Name
NM_024654.5 NP_078930.4 polynucleotide 5'-hydroxyl-kinase NOL9

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity IDA
IDA: Inferred from direct assay
21063389 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
Biological Process GO Annotation Evidence References Source
involved in maturation of 5.8S rRNA IMP
IMP: Inferred from mutant phenotype
21063389 GOA
Cellular Component GO Annotation Evidence References Source
located in nucleolus IDA
IDA: Inferred from direct assay
31288032 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

NOL9 Protein Structure

MobB

MobB: Molybdopterin guanine dinucleotide synthesis protein B (300 - 401)

Clp1

Clp1: Pre-mRNA cleavage complex II protein Clp1 (409 - 648)

  • 0
  • 200
  • 400
  • 600
  • 702 a.a.
Protein Preferred Names Protein Names

polynucleotide 5'-hydroxyl-kinase NOL9

  • polynucleotide 5'-kinase

NOL9 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
NOL9 Q5SY16 AHNAK Homo sapiens Q09666-2
Y2H Prey Pooling
25416956
Intra
NOL9 Q5SY16 AHNAK Homo sapiens Q09666-2
Validated Y2H
25416956
Intra
NOL9 Q5SY16 AHNAK Homo sapiens Q09666-2
Y2H Array
25416956
Intra
NOL9 Q5SY16 REL Homo sapiens Q04864
Validated Y2H
25416956
Intra
NOL9 Q5SY16 REL Homo sapiens Q04864
Y2H Array
25416956
Intra
NOL9 Q5SY16 REL Homo sapiens Q04864
Y2H Prey Pooling
25416956
Intra
NOL9 Q5SY16 TCF4 Homo sapiens P15884
Validated Y2H
25416956
Intra
NOL9 Q5SY16 TCF4 Homo sapiens P15884
Y2H Prey Pooling
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09419 NOL9 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus NOL9 MGD MGI:1921285
Canis familiaris NOL9 VGNC VGNC:53428
Macaca mulatta NOL9 VGNC VGNC:75263
Bos taurus NOL9 VGNC VGNC:32160
Rattus norvegicus NOL9 RGD RGD:1566167
Felis catus NOL9 VGNC VGNC:80294
Others NOL9 NCBI