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79735

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12

Inhibitors & Agonists

1

Inhibitory Antibodies

8

Antibodies

8

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P99405
    Prasinezumab

    PRX 002; RG 7935; RO 7046015

    		 α-synuclein Neurological Disease
    Prasinezumab (PRX 002) is a humanized IgG1 monoclonal antibody directed against aggregated α-synuclein. Prasinezumab has the potential for Parkinson's disease research .
    Prasinezumab
  • HY-12507
    GSK-7975A
    10+ Cited Publications

    		 Calcium Channel Inflammation/Immunology
    GSK-7975A is a potent and orally available CRAC channel inhibitor.
    GSK-7975A
  • HY-128337
    AN7973

    		Parasite Infection
    AN7973 is the 6-carboxamide benzoxaborole, blocks intracellular parasite development and inhibits Cryptosporidium growth. AN7973 is orally active, possesses favorable safety, stability, and PK parameters, and is an exciting agent candidate for treating cryptosporidiosis.
    AN7973
  • HY-155467
    MRS7935

    		Adenosine Receptor Endocrinology
    MRS7935 (compound 15) is an A1AR positive allosteric modulator (PAM) with an EC50 of approximately 2 μM .
    MRS7935
  • HY-R02439
    hsa-miR-7975 mimic

    		MicroRNA Cancer
    hsa-miR-7975 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
    hsa-miR-7975 mimic
    hsa-miR-7975 mimic
  • HY-R02437
    hsa-miR-7973 mimic

    		MicroRNA Cancer
    hsa-miR-7973 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
    hsa-miR-7973 mimic
    hsa-miR-7973 mimic
  • HY-RI02437
    hsa-miR-7973 inhibitor

    		MicroRNA Cancer
    hsa-miR-7973 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
    hsa-miR-7973 inhibitor
    hsa-miR-7973 inhibitor
  • HY-R02437A
    hsa-miR-7973 agomir

    		MicroRNA Cancer
    hsa-miR-7973 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    hsa-miR-7973 agomir
    hsa-miR-7973 agomir
  • HY-RI02439
    hsa-miR-7975 inhibitor

    		MicroRNA Cancer
    hsa-miR-7975 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
    hsa-miR-7975 inhibitor
    hsa-miR-7975 inhibitor
  • HY-RI02439A
    hsa-miR-7975 antagomir

    		MicroRNA Cancer
    hsa-miR-7975 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    hsa-miR-7975 antagomir
    hsa-miR-7975 antagomir
  • HY-R02439A
    hsa-miR-7975 agomir

    		MicroRNA Cancer
    hsa-miR-7975 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    hsa-miR-7975 agomir
    hsa-miR-7975 agomir
  • HY-RI02437A
    hsa-miR-7973 antagomir

    		MicroRNA Cancer
    hsa-miR-7973 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    hsa-miR-7973 antagomir
    hsa-miR-7973 antagomir

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