FRMD1 - FERM domain containing 1 Gene

Also Known as bA164L23.1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 79981

About FRMD1

This gene has 11 transcripts (splice variants) and 149 orthologues. Biased expression in colon (RPKM 2.7), kidney (RPKM 2.0) and 7 other tissues.

Summary

Predicted to be involved in positive regulation of hippo signaling. Predicted to be located in Cytoskeleton. Predicted to be active in cytoplasmic side of apical plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

FRMD1 Products (3)

mRNA Protein Name
NM_001122841.3 NP_001116313.1 FERM domain-containing protein 1 isoform 2
NM_001394681.1 NP_001381610.1 FERM domain-containing protein 1 isoform 3
NM_024919.6 NP_079195.3 FERM domain-containing protein 1 isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

FRMD1 Protein Structure

FERM_N

FERM_N: FERM N-terminal domain (58 - 147)

FERM_M

FERM_M: FERM central domain (153 - 264)

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  • 500
  • 549 a.a.
Protein Preferred Names Protein Names

FERM domain-containing protein 1

FRMD1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
FRMD1 Q8N878 RAB2A Homo sapiens P61019
Y2H Prey Pooling
32296183
Intra
FRMD1 Q8N878 RAB2A Homo sapiens P61019
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05099 FRMD1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus FRMD1 VGNC VGNC:102425
Rattus norvegicus FRMD1 RGD RGD:1588779
Bos taurus FRMD1 VGNC VGNC:56363
Macaca mulatta FRMD1 VGNC VGNC:72757
Others FRMD1 NCBI