SRCIN1 - SRC kinase signaling inhibitor 1 Gene

Also Known as P140; SNIP

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 80725

About SRCIN1

Cytogenetic location: 17q12 Genomic coordinates (GRCh38): 17:38,530,031-38,607,025 (from NCBI)

This gene has 9 transcripts (splice variants), 1 gene allele, 282 orthologues and 1 paralogue. Biased expression in brain (RPKM 9.1), salivary gland (RPKM 1.2) and 2 other tissues.

Summary

Enables protein kinase binding activity. Involved in several processes, including regulation of dendritic spine morphogenesis; regulation of protein tyrosine kinase activity; and substrate adhesion-dependent cell spreading. Located in actin Cytoskeleton and cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

SRCIN1 Products (1)

mRNA Protein Name
NM_025248.3 NP_079524.2 SRC kinase signaling inhibitor 1
Protein Preferred Names Protein Names

SRC kinase signaling inhibitor 1

  • P130Cas-associated protein

SRCIN1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
SRCIN1 Q9C0H9 SRC Homo sapiens P12931
Anti Bait CoIP
17525734
Intra
SRCIN1 Q9C0H9 BCAR1 Homo sapiens P56945
Confocal
14657239
Intra
SRCIN1 Q9C0H9 BCAR1 Homo sapiens P56945
Anti Bait CoIP
14657239
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Maxillary Sinus Inverted Papilloma

  • Inverted Papilloma Of The Maxillary Sinus
Maxillary Sinus Benign Neoplasm

  • Neoplasm Of Maxillary Sinus

  • Tumor Of Maxillofacial Sinus

  • Maxillary Sinus Neoplasms

  • Maxillary Sinus Neoplasm
Frontal Sinus Inverted Papilloma

  • Inverted Papilloma Of The Frontal Sinus
Larynx Squamous Papilloma

  • Laryngeal Squamous Cell Papilloma
Frontal Sinus Benign Neoplasm

  • Neoplasm Of Frontal Sinus

  • Tumor Of The Frontal Sinus
Inverted Papilloma

  • Inverted Papilloma, Squamous Cell

  • Papilloma Inverted

  • Papilloma, Inverted

  • Inverted Squamous Cell Papilloma
Bipolar I Disorder

  • Manic Depression Nos

  • Manic-Depressive Illness

  • Bipolar Disorder Nos
Paranoid Personality Disorder
Schizoaffective Disorder

  • Schizo-Affective Psychosis

  • Schizo-Affective Type Schizophrenia

  • Schizoaffective Psychosis

  • Schizoaffective Schizophrenia

  • Schizophrenia, Schizo-Affective Type

  • Schizophreniform Psychosis, Affective Type
Kohlschutter-Tonz Syndrome

  • Amelocerebrohypohidrotic Syndrome

  • KTZS

  • Epilepsy And Yellow Teeth

  • Kohlschutter Tonz Syndrome

  • Kohlschutter Syndrome

  • Epilepsy Dementia Amelogenesis Imperfecta

  • Epilepsy-Dementia-Amelogenesis Imperfecta Syndrome

  • Epilepsy, Dementia, And Amelogenesis Imperfecta

  • Kohlschutter'S Syndrome

  • Kohlschütter-Tönz Syndrome

  • Kohlschuetter-Toenz Syndrome

  • Presenile Dementia

  • Dementia
Myopathy, Centronuclear, 2

  • Myopathy, Centronuclear, Autosomal Recessive

  • Autosomal Recessive Centronuclear Myopathy

  • CNM2

  • Centronuclear Myopathy 2

  • Ar-Cnm

  • Myotubular Myopathy, Autosomal Recessive

  • Autosomal Recessive Myotubular Myopathy

  • Centronuclear Myopathy Autosomal Recessive

  • Myopathy, Centronuclear, Type 2
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-16905 T338C Src-IN-1 Inhibitor / Unkown
HY-RS13753 SRCIN1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta SRCIN1 VGNC VGNC:78012
Mus musculus SRCIN1 MGD MGI:1933179
Canis familiaris SRCIN1 VGNC VGNC:46792
Bos taurus SRCIN1 VGNC VGNC:35270
Felis catus SRCIN1 VGNC VGNC:65672
Rattus norvegicus SRCIN1 RGD RGD:708439
Others SRCIN1 NCBI