Erap1 - endoplasmic reticulum aminopeptidase 1 Gene

Also Known as Arts1; Appils

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 80897

Summary

Enables Aminopeptidase activity; tumor necrosis factor receptor binding activity; and zinc ion binding activity. Involved in proteolysis. Located in endoplasmic reticulum lumen. Human ortholog(s) of this gene implicated in cervix carcinoma. Orthologous to human ERAP1 (endoplasmic reticulum Aminopeptidase 1). [provided by Alliance of Genome Resources, Apr 2022]

Erap1 Products (1)

mRNA Protein Name
NM_001399166.1 NP_001386095.1 endoplasmic reticulum aminopeptidase 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables aminopeptidase activity IMP
IMP: Inferred from mutant phenotype
10824104 RGD
enables tumor necrosis factor receptor binding IPI
IPI: Inferred from physical interaction
20649583 RGD
enables zinc ion binding IMP
IMP: Inferred from mutant phenotype
10824104 RGD
Biological Process GO Annotation Evidence References Source
involved in protein catabolic process IMP
IMP: Inferred from mutant phenotype
10824104 RGD
Cellular Component GO Annotation Evidence References Source
located in endoplasmic reticulum lumen IDA
IDA: Inferred from direct assay
12436109 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

endoplasmic reticulum aminopeptidase 1

  • A-LAP

  • ARTS-1

  • ER-aminopeptidase 1

  • PILS-AP

  • adipocyte-derived leucine aminopeptidase

  • aminopeptidase PILS

  • leucyl-specific aminopeptidase PILS

  • puromycin-insensitive leucyl-specific aminopeptidase

  • type 1 tumor necrosis factor receptor shedding aminopept

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (16)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-133125 ERAP1-IN-1 Inhibitor 98.77% Unkown
HY-139907B DG013A formate Inhibitor 99.57% Unkown
HY-169915 ERAP1 modulator-2 Inhibitor 98.93% Unkown
HY-139907C DG013B formate Control / Unkown
HY-139907 DG013A Inhibitor / Unkown
HY-169913 ERAP1 modulator-1 Modulator / Unkown
HY-169936 ERAP1-IN-3 Inhibitor / Unkown
HY-173022 BDM_92499 Inhibitor / Unkown
HY-179625 GSK235 Inhibitor / Unkown
HY-183267 ERAP1-IN-4 Inhibitor / Unkown
HY-184499 GRWD5769 / Unkown
HY-RS04463 ERAP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-139907A DG013B Control / Unkown
HY-168181 ERAP1-IN-2 Inhibitor / Unkown
HY-RS17658 Erap1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24119 Erap1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Erap1 NCBI NCBI:51752