Erap1 - endoplasmic reticulum aminopeptidase 1 Gene

Also Known as A-LAP; Arts1; ERAAP; PILSA; ARTS-1; PILSAP

Species: Mus musculus

Gene Type: protein coding
Gene ID: 80898

Summary

Enables Aminopeptidase activity. Acts upstream of or within positive regulation of angiogenesis and proteolysis. Located in cytoplasm. Is expressed in several structures, including alimentary system; brain; genitourinary system; immune system; and respiratory system. Human ortholog(s) of this gene implicated in cervix carcinoma. Orthologous to human ERAP1 (endoplasmic reticulum Aminopeptidase 1). [provided by Alliance of Genome Resources, Apr 2022]

Erap1 Products (1)

mRNA Protein Name
NM_030711.5 NP_109636.1 endoplasmic reticulum aminopeptidase 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables aminopeptidase activity IDA
IDA: Inferred from direct assay
11964289 MGI
enables peptidase activity IMP
IMP: Inferred from mutant phenotype
23610143 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within positive regulation of angiogenesis IMP
IMP: Inferred from mutant phenotype
11964289 MGI
acts upstream of or within proteolysis IDA
IDA: Inferred from direct assay
23610143 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
11964289 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

endoplasmic reticulum aminopeptidase 1

  • VEGF-induced aminopeptidase

  • adipocyte-derived leucine aminopeptidase

  • aminopeptidase PILS

  • puromycin-insensitive leucyl-specific aminopeptidase

  • type 1 tumor necrosis factor receptor shedding aminopeptidase regulator

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (16)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-133125 ERAP1-IN-1 Inhibitor 98.77% Unkown
HY-139907B DG013A formate Inhibitor 99.57% Unkown
HY-169915 ERAP1 modulator-2 Inhibitor 98.93% Unkown
HY-139907C DG013B formate Control / Unkown
HY-139907 DG013A Inhibitor / Unkown
HY-169913 ERAP1 modulator-1 Modulator / Unkown
HY-169936 ERAP1-IN-3 Inhibitor / Unkown
HY-173022 BDM_92499 Inhibitor / Unkown
HY-179625 GSK235 Inhibitor / Unkown
HY-183267 ERAP1-IN-4 Inhibitor / Unkown
HY-184499 GRWD5769 / Unkown
HY-RS04463 ERAP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-139907A DG013B Control / Unkown
HY-168181 ERAP1-IN-2 Inhibitor / Unkown
HY-RS17658 Erap1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24119 Erap1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Erap1 NCBI NCBI:51752