Gpt - glutamic--pyruvic transaminase Gene

Also Known as ALAT; Gpt1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 81670

Summary

Involved in cellular response to Insulin stimulus; positive regulation of gluconeogenesis; and response to starvation. Located in cytoplasm and extracellular space. Biomarker of type 2 diabetes mellitus. Orthologous to human GPT (glutamic--pyruvic transaminase). [provided by Alliance of Genome Resources, Apr 2022]

Gpt Products (1)

mRNA Protein Name
NM_031039.2 NP_112301.1 alanine aminotransferase 1

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in cellular response to insulin stimulus IEP
IEP: Inferred from expression pattern
25865565 RGD
involved in positive regulation of gluconeogenesis IDA
IDA: Inferred from direct assay
25865565 RGD
involved in response to nutrient levels IEP
IEP: Inferred from expression pattern
25943649 RGD
involved in response to starvation IEP
IEP: Inferred from expression pattern
25865565 RGD
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
19085960 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

alanine aminotransferase 1

  • ALT1

  • GPT 1

  • glutamate pyruvate transaminase 1

  • glutamic pyruvate transaminase

  • glutamic pyruvic transaminase (alanine aminotrasferase)

  • glutamic pyruvic transaminase 1, soluble

  • glutamic--alanine transaminase 1

  • glutamic--pyruvic transaminase 1

  • glutamic

Recombinant Gpt Proteins

Cat. No. Product Name Accession Purity
HY-P75158 GPT Protein, Rat (sf9, His) P25409 (M1-S496) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-116509 Linoleylanilide Inhibitor / Phase 4

Pre-clinical Phase

Bioactive Molecules (13)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-A0098 Tunicamycin 99.96% Unkown
HY-137683A Guanosine 5'-O-2-thiodiphosphate trisodium Inhibitor 97.11% Unkown
HY-RS05762 GPT Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS05763 GPT2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS03945 DPAGT1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16893 Gpt2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-138616 dGTP 98.0% Unkown
HY-N13285 (-)-Epigallocatechin-4'-O-methylether / Unkown
HY-N15464 Antihepatotoxic agent-1 Inhibitor / Unkown
HY-N15587 Gostatin Inhibitor / Unkown
HY-RS17000 Gpt Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23335 Gpt2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23443 Gpt Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gpt NCBI NCBI:2875