Gostatin
Gostatin is an inhibitor of aspartate aminotransferase (GOT). Gostatin is found in Streptomyces sumanensis nov. sp. NK-23. Gostatin has a strong inhibitory effect on pig heart GOT, a weak inhibitory effect on wheat germ GOT and GPT, and no significant effect on glutamate dehydrogenase and glutamine synthetase. The inhibitory mechanism of gostatin is similar to substrate competitive inhibition, and aspartate has a protective effect on its inhibitory effect. Gostatin can be used to study the catalytic mechanism of GOT and its role in nitrogen metabolism.
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- CAS No.: 78416-84-9
- Formule: C8H10N2O5
- Masse moléculaire:214.18
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Chemical Information
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CAS No. 78416-84-9
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Masse moléculaire 214.18
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Formule C8H10N2O5
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SMILES
OC(CC1=C(NCC(C1=O)N)C(O)=O)=O
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Synonyms
Gostatine
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Structure Classification
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Initial Source
Streptomyces sumanensis nov. sp.
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)