Sp6 - trans-acting transcription factor 6 Gene

Also Known as Epfn; Klf14; 1110025J03Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 83395

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within positive regulation of cell population proliferation and regulation of odontogenesis. Located in nucleus. Is expressed in several structures, including branchial arch; genitourinary system; limb ectoderm; limb epithelium; and tooth. Orthologous to human SP6 (Sp6 transcription factor). [provided by Alliance of Genome Resources, Apr 2022]

Sp6 Products (2)

mRNA Protein Name
NM_001363230.1 NP_001350159.1 transcription factor Sp6
NM_031183.3 NP_112460.1 transcription factor Sp6

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in epithelial to mesenchymal transition IMP
IMP: Inferred from mutant phenotype
30504223 MGI
involved in odontogenesis IMP
IMP: Inferred from mutant phenotype
30504223 MGI
acts upstream of or within regulation of odontogenesis IMP
IMP: Inferred from mutant phenotype
18156176 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transcription factor Sp6

  • Kruppel-like factor 14

  • Sp6 transcription factor

  • epiprofin

  • krueppel-like factor 14

  • specificity protein 6

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-136893 SP-6-27 / Unkown
HY-P10092 SP6 Activator / Unkown
HY-RS13609 SP6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-137635 Sp-6-Phe-cAMPS Activator / Unkown
HY-RS18223 Sp6 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20514 Usp53 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24700 Sp6 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sp6 NCBI NCBI:80320