GSG1 - germ cell associated 1 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 83445

About GSG1

This gene has 10 transcripts (splice variants), 145 orthologues and 10 paralogues. Restricted expression toward testis (RPKM 69.4).

Summary

Predicted to enable RNA polymerase binding activity. Predicted to be located in endoplasmic reticulum membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

GSG1 Products (16)

mRNA Protein Name
NM_001080554.4 NP_001074023.1 germ cell-specific gene 1 protein isoform 3
NM_001080555.4 NP_001074024.1 germ cell-specific gene 1 protein isoform 4
NM_001206842.3 NP_001193771.1 germ cell-specific gene 1 protein isoform 5
NM_001206843.3 NP_001193772.1 germ cell-specific gene 1 protein isoform 6
NM_001206845.3 NP_001193774.1 germ cell-specific gene 1 protein isoform 7
NM_001367358.2 NP_001354287.1 germ cell-specific gene 1 protein isoform 8
NM_001367359.2 NP_001354288.1 germ cell-specific gene 1 protein isoform 9
NM_001367360.2 NP_001354289.1 germ cell-specific gene 1 protein isoform 10
NM_001367361.2 NP_001354290.1 germ cell-specific gene 1 protein isoform 11
NM_001367362.2 NP_001354291.1 germ cell-specific gene 1 protein isoform 12
NM_001367363.2 NP_001354292.1 germ cell-specific gene 1 protein isoform 13
NM_001367364.2 NP_001354293.1 germ cell-specific gene 1 protein isoform 14
NM_001367366.1 NP_001354295.1 germ cell-specific gene 1 protein isoform 15
NM_001368007.2 NP_001354936.1 germ cell-specific gene 1 protein isoform 16
NM_031289.5 NP_112579.2 germ cell-specific gene 1 protein isoform 1
NM_153823.5 NP_722545.2 germ cell-specific gene 1 protein isoform 2

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

GSG1 Protein Structure

GSG-1

GSG-1: GSG1-like protein (22 - 136)

  • 0
  • 100
  • 200
  • 300
  • 339 a.a.
Protein Preferred Names Protein Names

germ cell-specific gene 1 protein

  • testicular secretory protein Li 20

GSG1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
GSG1 Q2KHT4 TRAF2 Homo sapiens Q12933
Validated Y2H
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Epithelioid Cell Melanoma

  • Epithelioid Melanoma
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05860 GSG1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS05861 GSG1L Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14994 TRAPPC8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta GSG1 VGNC VGNC:73198
Bos taurus GSG1 VGNC VGNC:29676
Felis catus GSG1 VGNC VGNC:62728
Rattus norvegicus GSG1 RGD RGD:1306546
Mus musculus GSG1 MGD MGI:1194499
Canis familiaris GSG1 VGNC VGNC:41528
Others GSG1 NCBI