PUS7L - pseudouridine synthase 7 like Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 83448

Summary

Enables pseudouridine synthase activity. Involved in mRNA pseudouridine synthesis. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Jul 2025]
Ubiquitous expression in thyroid (RPKM 3.3), appendix (RPKM 2.8) and 25 other tissues.

PUS7L Products (4)

mRNA Protein Name
NM_001098614.3 NP_001092084.1 pseudouridylate synthase PUS7L isoform a
NM_001098615.2 NP_001092085.1 pseudouridylate synthase PUS7L isoform a
NM_001271826.2 NP_001258755.1 pseudouridylate synthase PUS7L isoform b
NM_031292.5 NP_112582.3 pseudouridylate synthase PUS7L isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
enables pseudouridine synthase activity IDA
IDA: Inferred from direct assay
35051350 GOA
Biological Process GO Annotation Evidence References Source
involved in mRNA pseudouridine synthesis IDA
IDA: Inferred from direct assay
35051350 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PUS7L Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
PUS7L Q9H0K6 TRIM27 Homo sapiens P14373
Y2H Array
32296183
Intra
PUS7L Q9H0K6 TRIM27 Homo sapiens P14373
Y2H Prey Pooling
25416956
Intra
PUS7L Q9H0K6 TRIM27 Homo sapiens P14373
Y2H Prey Pooling
32296183
Intra
PUS7L Q9H0K6 TRIM41 Homo sapiens Q8WV44
Y2H Array
25416956
Intra
PUS7L Q9H0K6 TRIM41 Homo sapiens Q8WV44
Y2H Prey Pooling
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11470 PUS7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS11471 PUSL1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20805 Pus7 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27319 Pus7 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown