QRFPR - pyroglutamylated RFamide peptide receptor Gene

Also Known as AQ27; GPR103; SP9155

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 84109

About QRFPR

Cytogenetic location: 4q27 Genomic coordinates (GRCh38): 4:121,328,642-121,381,018 (from NCBI)

This gene has 4 transcripts (splice variants), 214 orthologues and 16 paralogues. Low expression observed in reference dataset.

Summary

Enables G protein-coupled receptor activity. Involved in G protein-coupled receptor signaling pathway. Predicted to be located in non-motile cilium. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

QRFPR Products (1)

mRNA Protein Name
NM_198179.3 NP_937822.2 pyroglutamylated RF-amide peptide receptor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables G protein-coupled receptor activity IDA
IDA: Inferred from direct assay
12960173 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
Biological Process GO Annotation Evidence References Source
involved in G protein-coupled receptor signaling pathway IDA
IDA: Inferred from direct assay
12960173 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

QRFPR Protein Structure

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (62 - 332)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 431 a.a.
Protein Preferred Names Protein Names

pyroglutamylated RF-amide peptide receptor

  • G-protein coupled receptor 103

QRFPR Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
QRFPR Q96P65 NTM Homo sapiens Q9P121-3
Validated Y2H
32296183
Intra
QRFPR Q96P65 GJA8 Homo sapiens P48165
Y2H Array
32296183
Intra
QRFPR Q96P65 GJA8 Homo sapiens P48165
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11505 QRFPR Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris QRFPR VGNC VGNC:54347
Mus musculus QRFPR MGD MGI:2677633
Macaca mulatta QRFPR VGNC VGNC:76482
Bos taurus QRFPR VGNC VGNC:33601
Felis catus QRFPR VGNC VGNC:64458
Rattus norvegicus QRFPR RGD RGD:728380
Others QRFPR NCBI