POLDIP3 - DNA polymerase delta interacting protein 3 Gene

Homo sapiens

Also known as SKAR; PDIP3; PDIP46

Gene ID: 84271 | Gene type: protein coding

About POLDIP3

Cytogenetic location: 22q13.2 Genomic coordinates (GRCh38): 22:42,583,721-42,614,883 (from NCBI)

This gene has 8 transcripts (splice variants), 213 orthologues and 2 paralogues. Ubiquitous expression in ovary (RPKM 49.2), bone marrow (RPKM 26.9) and 25 other tissues.

Summary

This gene encodes an RRM (RNA recognition motif)-containing protein that participates in the regulation of translation by recruiting ribosomal protein S6 kinase beta-1 to mRNAs. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

POLDIP3 Products(4)

mRNA	Protein	Name
NM_001278657.2	NP_001265586.1	polymerase delta-interacting protein 3 isoform 3
NM_001363052.2	NP_001349981.1	polymerase delta-interacting protein 3 isoform 4
NM_032311.5	NP_115687.2	polymerase delta-interacting protein 3 isoform 1
NM_178136.3	NP_835237.1	polymerase delta-interacting protein 3 isoform 2

POLDIP3 Protein Structure

RRM_1

0
100
200
300
421 a.a.

Protein Preferred Names

Protein Names

polymerase delta-interacting protein 3

46 kDa DNA polymerase delta interaction protein

Related Diseases

Diseases

Alias

Methylmalonic Aciduria, Cblb Type

Methylmalonic Aciduria Cblb Type	Methylmalonic Acidemia Cblb Type
Methylmalonic Aciduria, Vitamin B12-Responsive, Due To Defect In Synthesis Of Adenosylcobalamin, Cblb Complementation Type	Methylmalonic Acidemia, Cblb Type
Methylmalonic Aciduria, Vitamin B12-Responsive, Due To Defect In Synthesis Of Adenosylcobalamin, Cblb Type	Methylmalonic Aciduria, Vitamin B12-Responsive, Cblb Type
Vitamin B12-Responsive Methylmalonic Acidemia Type Cblb	Vitamin B12-Responsive Methylmalonic Aciduria, Type Cblb
Methylmalonic Aciduria Type Cblb	MMAB
Methylmalonic Aciduria Type B	Vitamin B12 Responsive Methylmalonic Acidemia Type Cbl B
Vitamin B12 Responsive Methylmalonic Aciduria Type Cbl B	Aciduria, Methylmalonic, Cblb Type
Methylmalonic Acidemia	Methylmalonic Aciduria

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10824	POLDIP3 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	POLDIP3	MGD	MGI:1921076
Canis familiaris	POLDIP3	VGNC	VGNC:44778
Rattus norvegicus	POLDIP3	RGD	RGD:1311073
Macaca mulatta	POLDIP3	VGNC	VGNC:97119
Bos taurus	POLDIP3	VGNC	VGNC:33117
Felis catus	POLDIP3	VGNC	VGNC:64284

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