C7orf50 - chromosome 7 open reading frame 50 Gene

Also Known as YCR016W

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 84310

About C7orf50

This gene has 8 transcripts (splice variants) and 172 orthologues. Ubiquitous expression in kidney (RPKM 5.2), brain (RPKM 3.9) and 25 other tissues.

Summary

Enables RNA binding activity. [provided by Alliance of Genome Resources, Apr 2022]

C7orf50 Products (7)

mRNA Protein Name
NM_001134395.1 NP_001127867.1 uncharacterized protein C7orf50 isoform a
NM_001134396.1 NP_001127868.1 uncharacterized protein C7orf50 isoform a
NM_001318252.2 NP_001305181.1 uncharacterized protein C7orf50 isoform a
NM_001350968.1 NP_001337897.1 uncharacterized protein C7orf50 isoform b
NM_001350969.2 NP_001337898.1 uncharacterized protein C7orf50 isoform c
NM_001350970.1 NP_001337899.1 uncharacterized protein C7orf50 isoform d
NM_032350.5 NP_115726.1 uncharacterized protein C7orf50 isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables hormone activity IDA
IDA: Inferred from direct assay
38503280 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
Biological Process GO Annotation Evidence References Source
involved in negative regulation of cholesterol biosynthetic process IDA
IDA: Inferred from direct assay
38503280 GOA
Cellular Component GO Annotation Evidence References Source
is active in extracellular space IDA
IDA: Inferred from direct assay
38503280 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

C7orf50 Protein Structure

DUF2373

DUF2373: Uncharacterised conserved protein (DUF2373) (103 - 166)

  • 0
  • 100
  • 194 a.a.
Protein Preferred Names Protein Names

uncharacterized protein C7orf50

C7orf50 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
C7orf50 Q9BRJ6 WFS1 Homo sapiens O76024
Y2H Pooling
32814053
Intra
C7orf50 Q9BRJ6 WFS1 Homo sapiens O76024
Validated Y2H
32814053
Intra
C7orf50 Q9BRJ6 WFS1 Homo sapiens O76024
Y2H Array
32814053
Intra
C7orf50 Q9BRJ6 THAP1 Homo sapiens Q9NVV9
Y2H Prey Pooling
32296183
Intra
C7orf50 Q9BRJ6 THAP1 Homo sapiens Q9NVV9
Validated Y2H
32296183
Intra
C7orf50 Q9BRJ6 THAP1 Homo sapiens Q9NVV9
Y2H Array
25416956
Intra
C7orf50 Q9BRJ6 THAP1 Homo sapiens Q9NVV9
Y2H Array
32296183
Intra
C7orf50 Q9BRJ6 THAP1 Homo sapiens Q9NVV9
Y2H Prey Pooling
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Albinism, Oculocutaneous, Type V

  • OCA5

  • Oculocutaneous Albinism Type V

  • Oculocutaneous Albinism Type 5
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01754 C7orf50 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta C7orf50 VGNC VGNC:70609
Felis catus C7orf50 VGNC VGNC:80558
Rattus norvegicus C7orf50 RGD RGD:1566418
Mus musculus C7orf50 MGD MGI:1920462
Bos taurus C7orf50 VGNC VGNC:54411
Canis familiaris C7orf50 VGNC VGNC:54009
Others C7orf50 NCBI