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  2. RAB11FIP4 - RAB11 family interacting protein 4 Gene

RAB11FIP4 - RAB11 family interacting protein 4 Gene

Homo sapiens

Also known as FIP4-Rab11; RAB11-FIP4

Gene ID: 84440 | Gene type: protein coding

About RAB11FIP4

Cytogenetic location: 17q11.2 Genomic coordinates (GRCh38): 17:31,391,675-31,538,211 (from NCBI)

This gene has 11 transcripts (splice variants), 283 orthologues and 1 paralogue. Broad expression in brain (RPKM 25.4), testis (RPKM 6.0) and 17 other tissues.

Summary

The protein encoded by this gene interacts with RAB11 and is thought to be involved in bringing recycling endosome membranes to the cleavage furrow in late cytokinesis. Hypoxic conditions can lead to an upregulation of the encoded protein and enhance the metastatic potential of hepatocellular carcinoma. [provided by RefSeq, Oct 2016]

RAB11FIP4 Products(5)

mRNA Protein Name
NM_001303542.3 NP_001290471.2 rab11 family-interacting protein 4 isoform 2
NM_001346747.2 NP_001333676.1 rab11 family-interacting protein 4 isoform 3
NM_001346748.2 NP_001333677.1 rab11 family-interacting protein 4 isoform 4
NM_001346749.2 NP_001333678.1 rab11 family-interacting protein 4 isoform 5
NM_032932.6 NP_116321.2 rab11 family-interacting protein 4 isoform 1

RAB11FIP4 Protein Structure

RBD-FIP

RBD-FIP: FIP domain (596 - 636)

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  • 637 a.a.
Protein Preferred Names Protein Names

rab11 family-interacting protein 4

RAB11 family interacting protein 4 (class II)

Related Diseases

Diseases Alias
Chromosome 17q11.2 Deletion Syndrome

Nf1 Microdeletion Syndrome

17q11 Microdeletion Syndrome

Neurofibromatosis Type 1 Microdeletion Syndrome

Van Asperen Syndrome

Del(17)(Q11)

Monosomy 17q11

Chromosome 17q11.2 Deletion Syndrome, 1.4mb

Hepatocellular Carcinoma

Liver Cancer

Primary Liver Cancer

HCC

Hepatoma

Malignant Neoplasm Of Liver

Liver Neoplasms

Cancer, Hepatocellular

Liver Cell Carcinoma

Lcc

Hepatoblastoma, Somatic

Hepatic Cancer

Primary Malignant Neoplasm Of Liver

Rare Tumor Of Liver And Intrahepatic Biliary Tract

Hepatocellular Carcinoma, Somatic

Hepatocellular Carcinoma, Childhood Type, Somatic

Hepatocellular Cancer, Somatic

Ca Liver - Primary

Hepatic Neoplasm

Malignant Hepato-Biliary Neoplasm

Malignant Neoplasm Of Liver, Not Specified As Primary Or Secondary

Malignant Neoplasm Of Liver, Primary

Malignant Tumor Of Liver

Neoplasm Of Liver

Non-Resectable Primary Hepatic Malignant Neoplasm

Resectable Malignant Neoplasm Of Liver

Resectable Malignant Neoplasm Of The Liver

Primary Liver Carcinoma

Primary Malignant Liver Neoplasm

Primary Cancer Of Liver

Primary Tumor Of The Liver

Rare Tumor Of Liver And Ibt

Hepatocellular Cancer

Neoplasm Of The Liver

Carcinoma, Hepatocellular

Hepatomas

Liver Neoplasm

Liver Carcinoma

Liver And Intrahepatic Biliary Tract Carcinoma

Malignant Hepatobiliary Neoplasm

Adult Primary Hepatocellular Carcinoma

Hepatoblastoma

Carcinoma Of Liver

Malignant Liver Tumour

Malignant Hepatic Tumour

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Felis catus RAB11FIP4 VGNC VGNC:64470
Bos taurus RAB11FIP4 VGNC VGNC:33619
Mus musculus RAB11FIP4 MGD MGI:2442920
Macaca mulatta RAB11FIP4 VGNC VGNC:76571
Canis familiaris RAB11FIP4 VGNC VGNC:45251
Rattus norvegicus RAB11FIP4 RGD RGD:1305063