Trpc4 - transient receptor potential cation channel, subfamily C, member 4 Gene

Also Known as Trp4; Trrp4

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 84494

Summary

Enables Calcium Channel activity. Involved in calcium ion transport; regulation of action potential firing rate; and regulation of calcium ion transport. Located in cytoplasm. Is integral component of plasma membrane. Orthologous to human TRPC4 (transient receptor potential cation channel subfamily C member 4). [provided by Alliance of Genome Resources, Apr 2022]

Trpc4 Products (2)

mRNA Protein Name
NM_001083115.1 NP_001076584.1 short transient receptor potential channel 4 isoform beta
NM_080396.1 NP_536321.1 short transient receptor potential channel 4 isoform alpha

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables calcium channel activity IDA
IDA: Inferred from direct assay
11713258 RGD
Biological Process GO Annotation Evidence References Source
involved in calcium ion transport IDA
IDA: Inferred from direct assay
11713258 RGD
involved in positive regulation of store-operated calcium entry IMP
IMP: Inferred from mutant phenotype
24113457 RGD
involved in regulation of action potential firing rate IMP
IMP: Inferred from mutant phenotype
26988269 RGD
involved in regulation of calcium ion transport IMP
IMP: Inferred from mutant phenotype
12381092 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

short transient receptor potential channel 4

  • CCE1

  • capacitative calcium entry channel 1

  • transient receptor potential channel 4

  • transient receptor potential protein 4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-133168 Englerin A Activator 99.50% Unkown
HY-12949 ML204 Inhibitor 98.45% Unkown
HY-12949A ML204 hydrochloride Inhibitor 99.74% Unkown
HY-184164 JD03-02 Antagonist / Unkown
HY-146155 TRPC4/5-IN-1 Inhibitor / Unkown
HY-144429 TRPC5-IN-4 Inhibitor / Unkown
HY-173024 TRPC4/5-IN-3 Inhibitor 99.65% Unkown
HY-162090 TRPC antagonist 1 Antagonist / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Trpc4 NCBI NCBI:7223