BUD13 - BUD13 homolog Gene

Also Known as Cwc26; fSAP71

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 84811

About BUD13

This gene has 3 transcripts (splice variants) and 203 orthologues. Ubiquitous expression in testis (RPKM 10.5), lymph node (RPKM 6.1) and 25 other tissues.

Summary

Enables RNA binding activity. Involved in mRNA splicing, via spliceosome. Located in nucleoplasm. Part of U2-type precatalytic spliceosome. [provided by Alliance of Genome Resources, Apr 2022]

BUD13 Products (2)

mRNA Protein Name
NM_001159736.2 NP_001153208.1 BUD13 homolog isoform 2
NM_032725.4 NP_116114.1 BUD13 homolog isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
22365833 GOA
Biological Process GO Annotation Evidence References Source
involved in mRNA splicing, via spliceosome IDA
IDA: Inferred from direct assay
29360106 GOA
Cellular Component GO Annotation Evidence References Source
part of U2-type precatalytic spliceosome IDA
IDA: Inferred from direct assay
29360106 GOA
located in nucleus IDA
IDA: Inferred from direct assay
29360106 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

BUD13 Protein Structure

Bud13

Bud13: Pre-mRNA-splicing factor of RES complex (460 - 601)

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  • 619 a.a.
Protein Preferred Names Protein Names

BUD13 homolog

  • functional spliceosome-associated protein 71

BUD13 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
BUD13 Q9BRD0 GPKOW Homo sapiens Q92917
Y2H Prey Pooling
25416956
Intra
BUD13 Q9BRD0 GPKOW Homo sapiens Q92917
Anti Tag CoIP
22365833
Intra
BUD13 Q9BRD0 GPKOW Homo sapiens Q92917
Y2H
22365833
Intra
BUD13 Q9BRD0 GPKOW Homo sapiens Q92917
Y2H Array
25416956
Intra
BUD13 Q9BRD0 RBMX2 Homo sapiens Q9Y388
Y2H
22365833
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Abdominal Obesity-Metabolic Syndrome Quantitative Trait Locus 2

  • Abdominal Obesity-Metabolic Syndrome

  • Abdominal Obesity Metabolic Syndrome

  • Metabolic Syndrome X

  • Aoms2

  • Aoms1
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01684 BUD13 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris BUD13 VGNC VGNC:38568
Macaca mulatta BUD13 VGNC VGNC:82112
Rattus norvegicus BUD13 RGD RGD:1308076
Mus musculus BUD13 MGD MGI:2443443
Bos taurus BUD13 VGNC VGNC:26607
Felis catus BUD13 VGNC VGNC:60211
Others BUD13 NCBI