ZBTB45 - zinc finger and BTB domain containing 45 Gene

Also Known as ZNF499

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 84878

Summary

Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II; regulation of cytokine production; and regulation of immune system process. Predicted to be located in nucleus. Predicted to be active in nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025]
Ubiquitous expression in fat (RPKM 3.6), spleen (RPKM 2.9) and 25 other tissues.

ZBTB45 Products (5)

mRNA Protein Name
NM_001316978.2 NP_001303907.1 zinc finger and BTB domain-containing protein 45
NM_001316979.2 NP_001303908.1 zinc finger and BTB domain-containing protein 45
NM_001316981.2 NP_001303910.1 zinc finger and BTB domain-containing protein 45
NM_001316982.2 NP_001303911.1 zinc finger and BTB domain-containing protein 45
NM_032792.4 NP_116181.1 zinc finger and BTB domain-containing protein 45

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
enables sequence-specific double-stranded DNA binding IDA
IDA: Inferred from direct assay
28473536 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZBTB45 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
ZBTB45 Q96K62 BAG4 Homo sapiens O95429
Y2H Prey Pooling
32296183
Intra
ZBTB45 Q96K62 BAG4 Homo sapiens O95429
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15974 ZBTB4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15975 ZBTB40 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15976 ZBTB43 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15977 ZBTB46 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15978 ZBTB48 Human Pre-designed siRNA Set A Pre-designed Set / Unkown