country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

ZNF341 - zinc finger protein 341 Gene

Also Known as HIES3

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 84905

About ZNF341

Cytogenetic location: 20q11.22 Genomic coordinates (GRCh38): 20:33,731,996-33,792,269 (from NCBI)

This gene has 7 transcripts (splice variants), 206 orthologues and is associated with 1 phenotype. Ubiquitous expression in testis (RPKM 1.6), spleen (RPKM 1.5) and 25 other tissues.

Summary

Enables DNA binding activity and DNA-binding transcription activator activity. Predicted to be involved in regulation of transcription, DNA-templated. Located in nucleus. Implicated in hyper IgE recurrent Infection syndrome 3. [provided by Alliance of Genome Resources, Apr 2022]

ZNF341 Products (3)

mRNA	Protein	Name
NM_001282933.2	NP_001269862.1	zinc finger protein 341 isoform 1
NM_001282935.2	NP_001269864.1	zinc finger protein 341 isoform 3
NM_032819.5	NP_116208.3	zinc finger protein 341 isoform 2

Gene Ontology

Molecular Function
Cellular Component

Molecular Function GO Annotation	Evidence	References	Source
enables DNA binding	IDA IDA: Inferred from direct assay	29907690	GOA
enables DNA-binding transcription activator activity	IDA IDA: Inferred from direct assay	29907690	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	25416956	GOA

Cellular Component GO Annotation	Evidence	References	Source
located in nucleus	IDA IDA: Inferred from direct assay	29907690	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZNF341 Protein Structure

zf-C2H2_6

zf-H2C2_2

zf-C2H2_4

zf-C2H2_6

zf-C2H2

zf-C2H2_4

zf-H2C2_2

0
200
400
600
800
854 a.a.

Protein Preferred Names	Protein Names
zinc finger protein 341

ZNF341 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	ZNF341	Q9BYN7	C11orf68	Homo sapiens	Q9H3H3-3	Validated Y2H	32296183
Intra	ZNF341	Q9BYN7	KLHL38	Homo sapiens	Q2WGJ6	Y2H Array	25416956
Intra	ZNF341	Q9BYN7	CSTF2	Homo sapiens	P33240	Y2H Array	25416956
Intra	ZNF341	Q9BYN7	NTAQ1	Homo sapiens	Q96HA8	Validated Y2H	25416956
Intra	ZNF341	Q9BYN7	NTAQ1	Homo sapiens	Q96HA8	Y2H Prey Pooling	25416956

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases	Alias
Hyper-Ige Recurrent Infection Syndrome 3, Autosomal Recessive	HIES3
Hyper Ige Recurrent Infection Syndrome 3
Chronic Mucocutaneous Candidiasis	Candidiasis, Chronic Mucocutaneous Cmc Candidiasis Chronic Mucocutaneous
Immunodeficiency 63 With Lymphoproliferation And Autoimmunity	IMD63 Il2rb Deficiency Cd122 Deficiency Immunodeficiency 63 Interleukin 2 Receptor, Beta, Deficiency Of Deficiency Of Interleukin 2 Receptor Beta
Hyper Ige Recurrent Infection Syndrome 1	Job Syndrome Hyper-Ige Recurrent Infection Syndrome 1 Hyperimmunoglobulin E Syndrome Job'S Syndrome Recurring Cold Staphylococcal Abscesses Ige Syndromes Buckley Syndrome Hie - [Hyperimmunoglobulin E] Syndrome Job-Buckley Syndrome Quie-Hill Syndrome
Immunodeficiency 35	Tyrosine Kinase 2 Deficiency IMD35 Tyk2 Deficiency Autosomal Recessive Hyper-Ige Syndrome With Atypical Mycobacteriosis Susceptibility To Infection Due To Tyk2 Deficiency Hyper-Ige Syndrome With Atypical Mycobacteriosis, Autosomal Recessive Hies With Atypical Mycobacteriosis, Autosomal Recessive Autosomal Recessiv Hies With Atypical Mycobacteriosis Autosomal Recessive Hyper-Ige Syndrome Due To Tyk2 Deficiency Autosomal Recessive Hies With Atypical Mycobacteriosis
Immunodeficiency 11	Immunodeficiency 11a Severe Combined Immunodeficiency Due To Card11 Deficiency IMD11A Imd11 Card11 Immunodeficiency Scid Due To Card11 Deficiency Card11 Deficiency Immunodeficiency 11 A
Nail Disease	Nail Diseases Abnormality Of The Nail Nail Anomaly
T Cell And Nk Cell Immunodeficiency
Hepatic Venoocclusive Disease With Immunodeficiency	VODI Hepatic Veno-Occlusive Disease-Immunodeficiency Syndrome Hepatic Veno-Occlusive Disease With Immunodeficiency Familial Veno-Occlusive Disease With Immunodeficiency Veno-Occlusive Disease And Immunodeficiency Syndrome Vodi Syndrome Vodi - [Veno-Occlusive Disease Immunodeficiency] Syndrome
Phaeohyphomycosis	Infection By Dematiacious Fungi Phaehyphomycosis Phaeomycosis Pheohyphomycosis Infection By Dematiacious Fungi [Phaehyphomycosis] Dematiaceous Fungal Infection
Hyper Ige Syndrome	Hyper-Ige Syndrome Hyper Immunoglobulin E Syndrome Hies Hyper-Ige Recurrent Infection Syndrome Hyperimmunoglobulin E Syndrome Hyper Ige Job Syndrome Hartnup Disease
Omenn Syndrome	Histiocytic Medullary Reticulosis Severe Combined Immunodeficiency With Hypereosinophilia Combined Immunodeficiency With Hypereosinophilia Reticuloendotheliosis, Familial, With Eosinophilia Reticuloendotheliosis Familial With Eosinophilia Familial Reticuloendotheliosis Omenn'S Syndrome OS Malignant Histiocytosis

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS16128	ZNF341 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	ZNF341	VGNC	VGNC:37253
Mus musculus	ZNF341	MGD	MGI:2682937
Macaca mulatta	ZNF341	VGNC	VGNC:79001
Felis catus	ZNF341	VGNC	VGNC:67292
Rattus norvegicus	ZNF341	RGD	RGD:1564726
Canis familiaris	ZNF341	VGNC	VGNC:48705
Others	ZNF341	NCBI