YBX3 - Y-box binding protein 3 Gene

Also Known as CSDA; DBPA; CSDA1; ZONAB

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 8531

About YBX3

Cytogenetic location: 12p13.2 Genomic coordinates (GRCh38): 12:10,699,089-10,723,323 (from NCBI)

This gene has 18 transcripts (splice variants), 131 orthologues and 4 paralogues. Broad expression in testis (RPKM 175.4), skin (RPKM 131.9) and 23 other tissues.

Summary

Enables RNA binding activity. Involved in cellular hyperosmotic response; cellular response to tumor necrosis factor; and negative regulation of programmed cell death. Located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]

YBX3 Products (2)

mRNA	Protein	Name
NM_001145426.2	NP_001138898.1	Y-box-binding protein 3 isoform b
NM_003651.5	NP_003642.3	Y-box-binding protein 3 isoform a

YBX3 Protein Structure

CSD

0
100
200
300
372 a.a.

Protein Preferred Names	Protein Names
Y-box-binding protein 3	DNA-binding protein A

YBX3 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	YBX3	P16989	UXT	Homo sapiens	Q9UBK9-2	Anti Tag CoIP	37608570

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases	Alias
Lyme Disease	Lyme Borreliosis Lyme Neuroborreliosis Borreliosis Borrelia Burgdorferi Infection Neuroborreliosis Bannwarth Syndrome Bannworth'S Syndrome Neurological Lyme Disease B. Burgdorferi Infection Borreliosis, Lyme Infection By Borrelia Burgdorferi Infection Due To Borrelia Burgdorferi Sensu Lato Lym Borrelia Infections
Tick-Borne Relapsing Fever	Relapsing Fever, Tick-Borne Relapsing Fever Due To Any Borrelia Species Other Than Borrelia Recurrentis African Tick-Borne Fever
Tick Infestation	Tick Infestations
Acrodermatitis Chronica Atrophicans	Acrodermatitis Atrophicans Chronica Herxheimer Disease Primary Diffuse Atrophy
Relapsing Fever	Febris Recurrens Novy Febris Recurrens Novy Relapsing Fever
Bejel	Njovera Dichuchwa Nonvenereal Endemic Syphilis Endemic Syphilis Frenga Nonvenereal Syphilis Treponemal Infections Non-Venereal Endemic Syphilis Siti Skerljevo Belesh
Louse-Borne Relapsing Fever	Relapsing Fever, Louse-Borne Relapsing Fever Due To Borrelia Recurrentis
Leukodystrophy, Hypomyelinating, 2	Pmld1 Hypomyelinating Leukodystrophy 2 HLD2 Pelizaeus-Merzbacher-Like Disease 1 Pelizaeus-Merzbacher-Like Disease Due To Gjc2 Mutation Pelizaeus-Merzbacher-Like Disease Type 1 Pelizaeus-Merzbacher-Like Disease, 1 Pelizaeus Merzbacher Like Disease Pelizaeus-Merzbacher-Like Disease Pmld - Pelizaeus Merzbacher Like Disease Pelizaeus-Merzbacher-Like Disease Autosomal Recessive Type 1 Pmldar1 Leukodystrophy, Hypomyelinating, Type 2
Parasitic Ectoparasitic Infectious Disease	Ectoparasitic Infestations Ectoparasitism

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15918	YBX3 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS20351	Ybx3 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS26860	Ybx3 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	YBX3	VGNC	VGNC:37018
Felis catus	YBX3	VGNC	VGNC:67132
Canis familiaris	YBX3	VGNC	VGNC:48480
Mus musculus	YBX3	MGD	MGI:2137670
Rattus norvegicus	YBX3	RGD	RGD:621056
Macaca mulatta	YBX3	VGNC	VGNC:79428
Others	YBX3	NCBI