2. Gene
  3. THOC5 - THO complex subunit 5 Gene

THOC5 - THO complex subunit 5 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as Fmip; PK1.3; fSAP79; C22orf19

Gene ID: 8563 | Gene type: protein coding

About THOC5

Cytogenetic location: 22q12.2 Genomic coordinates (GRCh38): 22:29,505,879-29,553,757 (from NCBI)

This gene has 17 transcripts (splice variants) and 223 orthologues. Ubiquitous expression in testis (RPKM 10.3), endometrium (RPKM 6.9) and 25 other tissues.

Summary

Predicted to enable mRNA binding activity. Involved in several processes, including monocyte differentiation; negative regulation of DNA damage checkpoint; and viral mRNA export from host cell nucleus. Located in nucleoplasm. Part of THO complex part of transcription export complex. Colocalizes with chromosome, telomeric region. Implicated in breast carcinoma. [provided by Alliance of Genome Resources, Apr 2022]

THOC5 Products(4)

mRNA Protein Name
NM_001002877.2 NP_001002877.1 THO complex subunit 5 homolog
NM_001002878.1 NP_001002878.1 THO complex subunit 5 homolog
NM_001002879.1 NP_001002879.1 THO complex subunit 5 homolog
NM_003678.5 NP_003669.4 THO complex subunit 5 homolog

THOC5 Protein Structure

FimP

FimP: Fms-interacting protein (96 - 452)

  • 0
  • 200
  • 400
  • 600
  • 683 a.a.
Protein Preferred Names Protein Names

THO complex subunit 5 homolog

Fms-interacting protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14494 THOC5 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta THOC5 VGNC VGNC:79178
Felis catus THOC5 VGNC VGNC:80500
Bos taurus THOC5 VGNC VGNC:35841
Mus musculus THOC5 MGD MGI:1351333
Canis familiaris THOC5 VGNC VGNC:47351
Rattus norvegicus THOC5 RGD RGD:1304991