BUD31 - BUD31 homolog Gene

Also Known as G10; EDG2; Cwc14; EDG-2; fSAP17; YCR063W

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 8896

About BUD31

Cytogenetic location: 7q22.1 Genomic coordinates (GRCh38): 7:99,408,969-99,419,616 (from NCBI)

This gene has 9 transcripts (splice variants) and 222 orthologues. Ubiquitous expression in testis (RPKM 25.3), bone marrow (RPKM 23.9) and 25 other tissues.

Summary

Enables nuclear receptor binding activity and nuclear receptor coactivator activity. Involved in mRNA splicing, via spliceosome and positive regulation of Androgen Receptor activity. Located in nucleus. Part of U2-type catalytic step 2 spliceosome. Colocalizes with chromatin. [provided by Alliance of Genome Resources, Apr 2022]

BUD31 Products (3)

mRNA Protein Name
NM_001370407.1 NP_001357336.1 protein BUD31 homolog
NM_001370410.1 NP_001357339.1 protein BUD31 homolog
NM_003910.4 NP_003901.2 protein BUD31 homolog

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables nuclear receptor binding IDA
IDA: Inferred from direct assay
25091737 GOA
enables nuclear receptor coactivator activity IDA
IDA: Inferred from direct assay
25091737 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
25091737 GOA
Biological Process GO Annotation Evidence References Source
involved in mRNA splicing, via spliceosome IDA
IDA: Inferred from direct assay
28076346 GOA
involved in positive regulation of androgen receptor activity IDA
IDA: Inferred from direct assay
25091737 GOA
Cellular Component GO Annotation Evidence References Source
part of U2-type catalytic step 2 spliceosome IDA
IDA: Inferred from direct assay
28076346 GOA
located in chromatin IDA
IDA: Inferred from direct assay
25091737 GOA
located in nucleus IDA
IDA: Inferred from direct assay
28076346 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

BUD31 Protein Structure

G10

G10: G10 protein (1 - 143)

  • 0
  • 100
  • 144 a.a.
Protein Preferred Names Protein Names

protein BUD31 homolog

  • G10 maternal transcript homolog

BUD31 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
BUD31 P41223 KRTAP10-7 Homo sapiens P60409
Y2H Prey Pooling
32296183
Intra
BUD31 P41223 KRTAP10-7 Homo sapiens P60409
Validated Y2H
32296183
Intra
BUD31 P41223 KRTAP10-7 Homo sapiens P60409
Y2H Array
25416956
Intra
BUD31 P41223 KRTAP10-7 Homo sapiens P60409
Y2H Array
32296183
Intra
BUD31 P41223 MEOX2 Homo sapiens Q6FHY5
Validated Y2H
32296183
Intra
BUD31 P41223 MEOX2 Homo sapiens Q6FHY5
Y2H Prey Pooling
32296183
Intra
BUD31 P41223 MEOX2 Homo sapiens Q6FHY5
Y2H Array
32296183
Intra
BUD31 P41223 HOXA1 Homo sapiens P49639
Y2H Array
32296183
Intra
BUD31 P41223 HOXA1 Homo sapiens P49639
Y2H Prey Pooling
32296183
Intra
BUD31 P41223 HOXA1 Homo sapiens P49639
Validated Y2H
32296183
Intra
BUD31 P41223 PICK1 Homo sapiens Q9NRD5
Y2H Prey Pooling
32296183
Intra
BUD31 P41223 PICK1 Homo sapiens Q9NRD5
Validated Y2H
32296183
Intra
BUD31 P41223 PICK1 Homo sapiens Q9NRD5
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01686 BUD31 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22409 Bud31 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus BUD31 VGNC VGNC:26609
Macaca mulatta BUD31 VGNC VGNC:70441
Mus musculus BUD31 MGD MGI:2141291
Rattus norvegicus BUD31 RGD RGD:621103
Felis catus BUD31 VGNC VGNC:60213
Others BUD31 NCBI