GLB1L2 - galactosidase beta 1 like 2 Gene

Also Known as MST114; MSTP114

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 89944

About GLB1L2

This gene has 5 transcripts (splice variants), 297 orthologues and 3 paralogues. Broad expression in prostate (RPKM 28.1), thyroid (RPKM 21.3) and 17 other tissues.

Summary

Predicted to enable beta-galactosidase activity. Predicted to be involved in carbohydrate metabolic process. Predicted to be located in extracellular region. Predicted to be active in vacuole. [provided by Alliance of Genome Resources, Apr 2022]

GLB1L2 Products (5)

mRNA Protein Name
NM_001370460.1 NP_001357389.1 beta-galactosidase-1-like protein 2 isoform a
NM_001370461.1 NP_001357390.1 beta-galactosidase-1-like protein 2 isoform b precursor
NM_001370462.1 NP_001357391.1 beta-galactosidase-1-like protein 2 isoform c precursor
NM_001370463.1 NP_001357392.1 beta-galactosidase-1-like protein 2 isoform d precursor
NM_138342.4 NP_612351.2 beta-galactosidase-1-like protein 2 isoform b precursor

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

GLB1L2 Protein Structure

Glyco_hydro_35

Glyco_hydro_35: Glycosyl hydrolases family 35 (53 - 365)

  • 0
  • 100
  • 200
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  • 500
  • 600
  • 636 a.a.
Protein Preferred Names Protein Names

beta-galactosidase-1-like protein 2

GLB1L2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
GLB1L2 Q8IW92 CAMK2A Homo sapiens Q9UQM7
Validated Y2H
32296183
Intra
GLB1L2 Q8IW92 CAMK2A Homo sapiens Q9UQM7
Y2H Array
32296183
Intra
GLB1L2 Q8IW92 CAMK2A Homo sapiens Q9UQM7
Y2H Prey Pooling
32296183
Intra
GLB1L2 Q8IW92 CYSRT1 Homo sapiens A8MQ03
Y2H Prey Pooling
32296183
Intra
GLB1L2 Q8IW92 CYSRT1 Homo sapiens A8MQ03
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Spherocytosis, Type 4

  • Hereditary Spherocytosis Type 4

  • SPH4

  • Hs4

  • Spherocytosis, Hereditary, 4

  • Hereditary Spherocytosis 4

  • Spherocytosis 4
Cleft Palate, Isolated

  • Cleft Palate

  • Isolated Cleft Palate

  • CPI

  • Cp

  • Palatoschisis

  • Cleft Palate Isolated

  • Uranostaphyloschisis

  • Congenital Fissure Of Palate

  • Cleft Of Secondary Palate
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05465 GLB1L2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus GLB1L2 VGNC VGNC:54872
Macaca mulatta GLB1L2 VGNC VGNC:101089
Rattus norvegicus GLB1L2 RGD RGD:1564436
Mus musculus GLB1L2 MGD MGI:2388283
Others GLB1L2 NCBI