UBE3D - ubiquitin protein ligase E3D Gene

Also Known as H10BH; UBE2CBP; YJR141W; C6orf157

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 90025

Summary

Enables several functions, including cyclin binding activity; ribonuclease inhibitor activity; and ubiquitin-like protein conjugating enzyme binding activity. Involved in protein autoubiquitination; protein monoubiquitination; and protein polyubiquitination. Part of ubiquitin Ligase complex. Is active in cytosol. [provided by Alliance of Genome Resources, Jun 2026]
Low expression observed in reference dataset.

UBE3D Products (6)

mRNA Protein Name
NM_001304437.2 NP_001291366.1 E3 ubiquitin-protein ligase E3D isoform 2
NM_001350602.2 NP_001337531.1 E3 ubiquitin-protein ligase E3D isoform 2
NM_001350603.2 NP_001337532.1 E3 ubiquitin-protein ligase E3D isoform 3
NM_001350604.2 NP_001337533.1 E3 ubiquitin-protein ligase E3D isoform 3
NM_001410933.1 NP_001397862.1 E3 ubiquitin-protein ligase E3D isoform 4
NM_198920.3 NP_944602.1 E3 ubiquitin-protein ligase E3D isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Références Source
enables cyclin binding IPI
IPI: Inferred from physical interaction
15749827 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
27173435 GOA
enables ubiquitin protein ligase activity IDA
IDA: Inferred from direct assay
15749827 GOA
enables ubiquitin-like protein conjugating enzyme binding IPI
IPI: Inferred from physical interaction
15749827 GOA
Biological Process GO Annotation Evidence Références Source
involved in protein autoubiquitination IDA
IDA: Inferred from direct assay
15749827 GOA
involved in protein monoubiquitination IDA
IDA: Inferred from direct assay
15749827 GOA
involved in protein polyubiquitination IDA
IDA: Inferred from direct assay
15749827 GOA
Cellular Component GO Annotation Evidence Références Source
part of ubiquitin ligase complex IDA
IDA: Inferred from direct assay
15749827 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

UBE3D Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Références
Intra
UBE3D Q7Z6J8 MAGEA11 Homo sapiens P43364
Y2H Prey Pooling
32296183
Intra
UBE3D Q7Z6J8 MAGEA11 Homo sapiens P43364
Y2H Array
32296183
Intra
UBE3D Q7Z6J8 DNAAF2 Homo sapiens Q9NVR5
Anti Tag CoIP
33961781
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS15370 UBE3C Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15368 UBE3A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15369 UBE3B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20508 Ube3a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22892 Ube3c Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27016 Ube3a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29406 Ube3c Rat Pre-designed siRNA Set A Pre-designed Set / Unkown