5 Results for "

90874

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "90874" in MCE Product Catalog:

7
7 Cited Publications
Cat. No.: HY-17473
CAS No.: 550-24-3
Synonyms: Embelic acid; Emberine; NSC 91874
Embelin (Embelic acid), a potent, nonpeptidic XIAP inhibitor (IC50=4.1 μM), inhibits cell growth, induces apoptosis, and activates caspase-9 in prostate cancer cells with high levels of XIAP. Embelin blocks NF-kappaB signaling pathway leading to suppression of NF-kappaB-regulated antiapoptotic and metastatic gene products. Embelin also induces autophagic and apoptotic cell death in human oral squamous cell carcinoma cells .
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Cat. No.: HY-17473R
CAS No.: 550-24-3
Synonyms: Embelic acid (Standard); Emberine (Standard); NSC 91874 (Standard)
Embelin (Standard) is the analytical standard of Embelin. This product is intended for research and analytical applications. Embelin (Embelic acid), a potent, nonpeptidic XIAP inhibitor (IC50=4.1 μM), inhibits cell growth, induces apoptosis, and activates caspase-9 in prostate cancer cells with high levels of XIAP. Embelin blocks NF-kappaB signaling pathway leading to suppression of NF-kappaB-regulated antiapoptotic and metastatic gene products. Embelin also induces autophagic and apoptotic cell death in human oral squamous cell carcinoma cells .
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Cat. No.: HY-100279
CAS No.: 38020-45-0
Target:  

Antibiotic

Research Areas:  

Infection Cancer

RMI 10874 is a tilorone analogue. Tilorone is a small-molecule, orally bioavailable antiviral agent. RMI 10874 completely abolishes lung colonization of an H-2 negative (GR9.B9) MCA-induced fibrosarcoma clone.
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Cat. No.: HY-129516
CAS No.: 131449-37-1
Research Areas:  

Metabolic Disease

A-70874 is a tyrosine-free tetrapeptide analog of cholecystokinin (30-33) (CCK-4). A-70874 is an agonist that stimulates pancreatic amylase release and a partial agonist that stimulates pancreatic phosphoinositide decomposition. A-70874 has an IC50 of 4.9 nM for the guinea pig pancreatic CCK receptor. Cholecystokinin (CCK) receptors are divided into CCK-A (digestive tract) and CCK-B (brain). A-70874 has an affinity of 1.6 μM for the CCK-B/gastrin receptor .
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Cat. No.: HY-P810612
Synonyms: ERBB3; HER3; Receptor tyrosine-protein kinase erbB-3; Proto-oncogene-like protein c-ErbB-3; Tyrosine kinase-type cell surface receptor HER3

Host:  

Rabbit

Application:  

WB, IHC-P

Reactivity:  

Human

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