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91368

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6

Inhibitors & Agonists

2

Natural
Products

1

Recombinant Proteins

1

Isotope-Labeled Compounds

5

Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B0751
    Fumagillin
    1 Publications Verification

    Amebacilin; NSC9168

    		 Parasite HIV Antibiotic Infection
    Fumagillin(NSC9168) is an antimicrobial compound first isolated in 1949 from the fungus Aspergillus fumigatu. Fumagillin can inhibits HIV‐1 infection through the inhibition of HIV-1 viral protein R (Vpr) activity.
    Fumagillin
  • HY-149878
    BD-9136

    		PROTACs Epigenetic Reader Domain Cancer
    BD-9136 is a potent and highly selective BRD4 PROTAC depressant. BD-9136 has low-nanomolar degradation potencies against BRD4 , and its degradation selectivity for BRD4 is 1000 times that of BRD2 and BRD3 proteins. BD-9136 has antitumor activity .(Pink: Desmethyl-QCA276 (HY-44103); Black: 3-(2-(4-Methylpiperazin-1-yl)ethyl)azetidin-3-ol; Blue: Thalidomide-4-OH (HY-103596))
    BD-9136
  • HY-B0751R
    Fumagillin (Standard)

    Amebacilin (Standard); NSC9168 (Standard)

    		 Reference Standards Parasite HIV Antibiotic Infection
    Fumagillin (Standard) is the analytical standard of Fumagillin. This product is intended for research and analytical applications. Fumagillin(NSC9168) is an antimicrobial compound first isolated in 1949 from the fungus Aspergillus fumigatu. Fumagillin can inhibits HIV‐1 infection through the inhibition of HIV-1 viral protein R (Vpr) activity.
    Fumagillin (Standard)
  • HY-100125A
    Timegadine hydrochloride

    SR1368 hydrochloride

    		 COX Inflammation/Immunology
    Timegadine hydrochloride (SR1368 hydrochloride) is the hydrochloride salt form of Timegadine (HY-100125). Timegadine hydrochloride is an orally active inhibitor for COX and lipo-oxygenase, that inhibits COX in washed rabbit platelets and rat brain with IC50 of 5 nM and 20 μM, inhibits lipo-oxygenase in in horse and washed rabbit platelets with IC50 of 100 μM. Timegadine hydrochloride exhibits anti-arthritis activity .
    Timegadine hydrochloride
  • HY-100125
    Timegadine

    SR1368

    		 COX Inflammation/Immunology
    Timegadine, a new antiinflammatory agent, is found to be a potent, competitive inhibitor of cyclo-oxygenase (COX) and lipo-oxygenase, with IC50s ranging from 5 nM (washed rabbit platelets) to 20 μM (rat brain) for COX and 100 μM for lipo-oxygenase both in the cytosol fraction of horse platelet homogenates, and in washed rabbit platelets.
    Timegadine
  • HY-B0751S
    Fumagillin-13C26

    Amebacilin-13C26; NSC9168-13C26

    		 Isotope-Labeled Compounds Infection
    Fumagillin- 13C26 (Amebacilin- 13C26) is the 13C-labeled Fumagillin (HY-B0751). Fumagillin(NSC9168) is an antimicrobial compound first isolated in 1949 from the fungus Aspergillus fumigatu. Fumagillin can inhibits HIV‐1 infection through the inhibition of HIV-1 viral protein R (Vpr) activity.
    Fumagillin-13C26

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