TMSB10 - thymosin beta 10 Gene

Also Known as TB10; MIG12

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 9168

About TMSB10

Cytogenetic location: 2p11.2 Genomic coordinates (GRCh38): 2:84,905,656-84,906,671 (from NCBI)

This gene has 1 transcript (splice variant) and 67 orthologues. Ubiquitous expression in appendix (RPKM 826.8), colon (RPKM 808.9) and 25 other tissues.

Summary

Predicted to enable actin monomer binding activity. Predicted to be involved in regulation of cell migration and sequestering of actin monomers. Predicted to be located in Cytoskeleton. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

TMSB10 Products (1)

mRNA Protein Name
NM_021103.4 NP_066926.1 thymosin beta-10

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
21044950 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TMSB10 Protein Structure

Thymosin

Thymosin: Thymosin beta-4 family (2 - 41)

  • 0
  • 44 a.a.
Protein Preferred Names Protein Names

thymosin beta-10

  • migration-inducing gene 12

TMSB10 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
TMSB10 P63313 KRTAP9-2 Homo sapiens Q9BYQ4
Validated Y2H
25416956
Intra
TMSB10 P63313 ALAS1 Homo sapiens P13196
Y2H Prey Pooling
25416956
Intra
TMSB10 P63313 ALAS1 Homo sapiens P13196
Y2H Prey Pooling
32296183
Intra
TMSB10 P63313 ALAS1 Homo sapiens P13196
Y2H Array
25416956
Intra
TMSB10 P63313 ALAS1 Homo sapiens P13196
Y2H Array
32296183
Intra
TMSB10 P63313 POT1 Homo sapiens Q9NUX5
Pull Down
21044950
Intra
TMSB10 P63313 POT1 Homo sapiens Q9NUX5
BiFC
21044950
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Diamond-Blackfan Anemia 5

  • DBA5

  • Rpl35a-Related Diamond-Blackfan Anemia

  • Anemia, Diamond-Blackfan, Type 5
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14774 TMSB10 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta TMSB10 VGNC VGNC:106240
Mus musculus TMSB10 MGD MGI:109146
Rattus norvegicus TMSB10 RGD RGD:62022
Others TMSB10 NCBI