LIN52 - lin-52 DREAM MuvB core complex component Gene

Also Known as C14orf46; c14_5549

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 91750

About LIN52

This gene has 5 transcripts (splice variants) and 210 orthologues. Low expression observed in reference dataset.

Summary

Predicted to be involved in transcription, DNA-templated. Predicted to be located in nucleoplasm. Predicted to be part of DRM complex. [provided by Alliance of Genome Resources, Apr 2022]

LIN52 Products (3)

mRNA Protein Name
NM_001024674.3 NP_001019845.2 protein lin-52 homolog isoform 1
NM_001372005.1 NP_001358934.1 protein lin-52 homolog isoform 2
NM_001372006.1 NP_001358935.1 protein lin-52 homolog isoform 3

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

LIN52 Protein Structure

LIN52

LIN52: Retinal tissue protein (18 - 112)

  • 0
  • 100
  • 116 a.a.
Protein Preferred Names Protein Names

protein lin-52 homolog

  • lin-52 homolog

LIN52 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
LIN52 Q52LA3 MAGEA6 Homo sapiens P43360
Y2H Prey Pooling
32296183
Intra
LIN52 Q52LA3 MAGEA6 Homo sapiens P43360
Y2H Array
32296183
Intra
LIN52 Q52LA3 EPM2AIP1 Homo sapiens Q7L775
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Abdominal Obesity-Metabolic Syndrome 3

  • AOMS3

  • Central Obesity, Type 2 Diabetes, Hypertension, And Early-Onset Coronary Artery Disease

  • Obesity, Abdominal, Metabolic Syndrome, Type 3
Intellectual Developmental Disorder, Autosomal Dominant 7

  • MRD7

  • Mental Retardation, Autosomal Dominant 7

  • Autosomal Dominant Non-Syndromic Intellectual Disability 7

  • Dyrk1a Syndrome

  • Autosomal Dominant Intellectual Developmental Disorder 7

  • Autosomal Dominant Mental Retardation 7

  • Mental Retardation, Autosomal Dominant, Type 7
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07674 LIN52 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris LIN52 VGNC VGNC:50543
Felis catus LIN52 VGNC VGNC:104484
Macaca mulatta LIN52 VGNC VGNC:108314
Mus musculus LIN52 MGD MGI:3045391
Rattus norvegicus LIN52 RGD RGD:1306798
Bos taurus LIN52 VGNC VGNC:30893
Others LIN52 NCBI