TIMD4 - T cell immunoglobulin and mucin domain containing 4 Gene

Also Known as TIM4; SMUCKLER

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 91937

About TIMD4

Cytogenetic location: 5q33.3 Genomic coordinates (GRCh38): 5:156,919,292-156,963,226 (from NCBI)

This gene has 3 transcripts (splice variants), 162 orthologues and 3 paralogues. Biased expression in lymph node (RPKM 8.4), testis (RPKM 2.6) and 5 other tissues.

Summary

Predicted to enable phosphatidylserine binding activity. Predicted to act upstream of or within apoptotic cell clearance. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

TIMD4 Products (2)

mRNA Protein Name
NM_001146726.2 NP_001140198.1 T-cell immunoglobulin and mucin domain-containing protein 4 isoform 2 precursor
NM_138379.3 NP_612388.2 T-cell immunoglobulin and mucin domain-containing protein 4 isoform 1 precursor

TIMD4 Protein Structure

V-set

V-set: Immunoglobulin V-set domain (22 - 117)

  • 0
  • 100
  • 200
  • 300
  • 378 a.a.
Protein Preferred Names Protein Names

T-cell immunoglobulin and mucin domain-containing protein 4

  • T-cell immunoglobulin mucin receptor 4

Recombinant TIMD4 Proteins

Cat. No. Product Name Accession Purity
HY-P70976 TIM-4/TIMD-4 Protein, Human (HEK293, His) AAH08988.1 (E25-L315) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P75552 TIM-4/TIMD-4 Protein, Human (Biotinylated, HEK293, His) AAH08988.1 (E25-L315) ≥ 90%, as determined by reducing SDS-PAGE.

TIMD4 Antibodies

Cat. No. Product Name Application Reactivity
HY-P84730 TIMD4 Antibody (YA4427) ICC/IF, FC, ELISA Human
HY-P84730A TIMD4 Antibody (YA4427)(PBS only) ICC/IF, FC, ELISA Human
HY-P84731 TIMD4 Antibody (YA4428) WB, FC, ELISA Human
HY-P84731A TIMD4 Antibody (YA4428)(PBS only) WB, FC, ELISA Human

Related Diseases

Diseases Alias
Histiocytic Sarcoma

  • Malignant Histiocytosis
Langerhans Cell Sarcoma

  • Malignant Langerhans Cell Sarcoma
Malaria

  • Malaria, Susceptibility To

  • Malaria, Resistance To

  • Malaria, Cerebral

  • Cerebral Malaria

  • Malaria, Severe, Susceptibility To

  • Malaria, Severe, Resistance To

  • Malaria, Cerebral, Susceptibility To

  • Induced Malaria

  • Malaria, Vivax, Protection Against

  • Malaria, Severe

  • Malaria, Cerebral, Reduced Risk Of

  • Malaria, Protection Against

  • Resistance To Malaria Due To G6pd Deficiency

  • Malaria Due To G6pd Deficiency

  • Malarial Encephalitis

  • CM

  • Malaria Cerebral

  • Susceptibility To Malaria

  • Acute Pernicious Fever

  • Aestivo-Autumnal Fever

  • Aestivo Autumnal Malaria

  • Chagres Fever

  • Continued Malaria Fever

  • Estivo-Autumnal Fever

  • Estivo-Autumnal Malaria

  • Estivo-Autumnal Malarial Fever

  • Falciparum Fever

  • Malignant Tertian Fever

  • Malignant Tertian Malaria

  • Pernicious Intermittent Fever

  • Pernicious Malaria

  • Quotidian Malaria

  • Subtertian Fever

  • Subtertian Malaria Fever

  • Subtertian Malignant Tertian Malaria

  • Tropical Malaria

  • Algid Malaria

  • Bilious Haemoglobinuric Fever

  • Black Water Fever

  • Blackwater Fever

  • Malarial Blackwater Fever

  • Severe Malarial Falciparum

  • West African Fever

  • Malarial Haematinuria

  • Haemoglobinuric Fever

  • Haemoglobinuric Malaria

  • Severe Plasmodium Falciparum Malaria

  • Malarial Haemoglobinuria

  • Malarial Haematuria

  • Falciparum Malaria [Malignant Tertian]

  • Malaria Tropica

  • Malarial Shock

  • Chagres Virus Disease

  • Malignant Malaria

  • Mtm - [Malignant Tertian Malaria]

  • Tm -[Malignant Tertian Malaria]

  • Panama Fever

  • St - [Subtertian Malaria]

  • Malarial Quotidian

  • Benign Tertian Malaria

  • Tertian Ague

  • Vivax Fever

  • Plasmodium Vivax Malaria Nos

  • Btm - [Benign Tertian Malaria]

  • Bt - [Benign Tertian Malaria]

  • Vivax Malaria

  • Benign Tertian Vivax Malaria

  • Tertian Malaria

  • Quartan Malaria

  • Quartan Ague

  • Quartan Fever

  • Plasmodium Malariae Malaria Nos

  • Quartan Malarial

  • Malaria By Plasmodium Malariae

  • Malariae Malaria

  • Ovale Tertian Malaria

  • Plasmodium Ovale Fever

  • Malaria Fever By Plasmodium Ovale

  • Ovale Malaria

  • Malaria By Plasmodium Ovale

  • Malarial Ovale

  • Marsh Fever

  • Remittent Congestive Fever

  • Coastal Fever

  • Remittent Gastric Fever

  • Miasmatic Fever

  • Congestive Remittent Fever

  • Intermittent Fever

  • Jungle Fever

  • Paludism

  • Cameroon Fever

  • Ague

  • Corsican Fever

  • Intermittent Bilious Fever

  • Disease Due To Plasmodiidae

  • Malarial Fever

  • Plasmodiosis

  • Remittent Fever

  • Roman Fever

  • Malaria Fever Nos

  • Malaria Nos

  • Paludal Fever

  • Clinically Diagnosed Malaria

  • Clinically Diagnosed Malaria Without Parasitological Confirmation

  • Congestive Fever

  • Malarial Cachexia

  • Marsh Cachexia

  • Paludal Cachexia

  • Recurrent Malaria

  • Remittent Malaria
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14525 TIMD4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18301 Timd4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24779 Timd4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus TIMD4 VGNC VGNC:102345
Bos taurus TIMD4 VGNC VGNC:55313
Rattus norvegicus TIMD4 RGD RGD:1564516
Mus musculus TIMD4 MGD MGI:2445125
Macaca mulatta TIMD4 VGNC VGNC:79477
Canis familiaris TIMD4 VGNC VGNC:51911
Others TIMD4 NCBI