ZMYM4 - zinc finger MYM-type containing 4 Gene

Also Known as MYM; CDIR; ZNF262; ZNF198L3

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 9202

About ZMYM4

Cytogenetic location: 1p34.3 Genomic coordinates (GRCh38): 1:35,268,709-35,422,058 (from NCBI)

This gene has 6 transcripts (splice variants), 132 orthologues and 18 paralogues. Ubiquitous expression in testis (RPKM 15.0), ovary (RPKM 10.1) and 25 other tissues.

Summary

Predicted to enable DNA binding activity. Involved in Cytoskeleton organization and regulation of cell morphogenesis. [provided by Alliance of Genome Resources, Apr 2022]

ZMYM4 Products (5)

mRNA Protein Name
NM_001350138.2 NP_001337067.1 zinc finger MYM-type protein 4 isoform 2
NM_001350139.2 NP_001337068.1 zinc finger MYM-type protein 4 isoform 3
NM_001350140.2 NP_001337069.1 zinc finger MYM-type protein 4 isoform 3
NM_001375653.1 NP_001362582.1 zinc finger MYM-type protein 4 isoform 4
NM_005095.3 NP_005086.2 zinc finger MYM-type protein 4 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
Biological Process GO Annotation Evidence References Source
involved in cytoskeleton organization IMP
IMP: Inferred from mutant phenotype
21834987 GOA
involved in regulation of cell morphogenesis IMP
IMP: Inferred from mutant phenotype
21834987 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZMYM4 Protein Structure

zf-FCS

zf-FCS: MYM-type Zinc finger with FCS sequence motif (335 - 373)

zf-FCS

zf-FCS: MYM-type Zinc finger with FCS sequence motif (382 - 425)

zf-FCS

zf-FCS: MYM-type Zinc finger with FCS sequence motif (479 - 521)

zf-FCS

zf-FCS: MYM-type Zinc finger with FCS sequence motif (683 - 719)

zf-FCS

zf-FCS: MYM-type Zinc finger with FCS sequence motif (722 - 760)

DUF3504

DUF3504: Domain of unknown function (DUF3504) (1354 - 1527)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1548 a.a.
Protein Preferred Names Protein Names

zinc finger MYM-type protein 4

  • cell death inhibiting RNA

ZMYM4 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
ZMYM4 Q5VZL5 ROR2 Homo sapiens A1L4F5
Validated Y2H
25416956
Intra
ZMYM4 Q5VZL5 ROR2 Homo sapiens A1L4F5
Y2H Prey Pooling
25416956
Intra
ZMYM4 Q5VZL5 ROR2 Homo sapiens A1L4F5
Y2H Array
25416956
Intra
ZMYM4 Q5VZL5 UBQLN1 Homo sapiens Q9UMX0-2
Y2H Array
25416956
Intra
ZMYM4 Q5VZL5 UBQLN1 Homo sapiens Q9UMX0-2
Validated Y2H
25416956
Intra
ZMYM4 Q5VZL5 RUNX1T1 Homo sapiens Q06455-4
Validated Y2H
25416956
Intra
ZMYM4 Q5VZL5 FHL2 Homo sapiens Q14192
Y2H Array
25416956
Intra
ZMYM4 Q5VZL5 FHL2 Homo sapiens Q14192
Y2H Prey Pooling
25416956
Intra
ZMYM4 Q5VZL5 UBQLN1 Homo sapiens Q9UMX0
Validated Y2H
25416956
Intra
ZMYM4 Q5VZL5 UBQLN1 Homo sapiens Q9UMX0
Y2H Array
25416956
Intra
ZMYM4 Q5VZL5 CTCF Homo sapiens P49711
Y2H Prey Pooling
25416956
Intra
ZMYM4 Q5VZL5 CTCF Homo sapiens P49711
Validated Y2H
25416956
Intra
ZMYM4 Q5VZL5 CTCF Homo sapiens P49711
Y2H Array
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Parkinson Disease 20, Early-Onset

  • Early-Onset Parkinson Disease 20

  • PARK20

  • Parkinson'S Disease 20

  • Early-Onset Parkinson'S Disease 20

  • Parkinson Disease, Type 20, Early-Onset
Non-Syndromic X-Linked Intellectual Disability

  • X-Linked Non-Syndromic Intellectual Disability

  • Non-Specific X-Linked Mental Retardation

  • X-Linked Non-Specific Intellectual Disability
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS16091 ZMYM4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus ZMYM4 MGD MGI:1915035
Felis catus ZMYM4 VGNC VGNC:67260
Macaca mulatta ZMYM4 VGNC VGNC:78887
Rattus norvegicus ZMYM4 RGD RGD:1309545
Bos taurus ZMYM4 VGNC VGNC:37200
Canis familiaris ZMYM4 VGNC VGNC:48648
Others ZMYM4 NCBI