2. Gene
  3. TCEAL1 - transcription elongation factor A like 1 Gene

TCEAL1 - transcription elongation factor A like 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as p21; SIIR; WEX9; pp21

Gene ID: 9338 | Gene type: protein coding

About TCEAL1

Cytogenetic location: Xq22.2 Genomic coordinates (GRCh38): X:103,628,716-103,630,953 (from NCBI)

This gene has 4 transcripts (splice variants), 82 orthologues and 8 paralogues. Ubiquitous expression in ovary (RPKM 48.1), endometrium (RPKM 41.3) and 24 other tissues.

Summary

This gene encodes a member of the transcription elongation factor A (SII)-like (TCEAL) gene family. Members of this family may function as nuclear phosphoproteins that modulate transcription in a promoter context-dependent manner. The encoded protein is similar to transcription elongation factor A/transcription factor SII and contains a zinc finger-like motif as well as a sequence related to the transcription factor SII Pol II-binding region. It may exert its effects via protein-protein interactions with other transcriptional regulators rather than via direct binding of DNA. Multiple family members are located on the X chromosome. Alternative splicing results in multiple transcript variants encoding a single isoform. [provided by RefSeq, Jul 2008]

TCEAL1 Products(3)

mRNA Protein Name
NM_001006639.2 NP_001006640.1 transcription elongation factor A protein-like 1
NM_001006640.2 NP_001006641.1 transcription elongation factor A protein-like 1
NM_004780.3 NP_004771.2 transcription elongation factor A protein-like 1

TCEAL1 Protein Structure

BEX

BEX: Brain expressed X-linked like family (1 - 158)

  • 0
  • 100
  • 159 a.a.
Protein Preferred Names Protein Names

transcription elongation factor A protein-like 1

TCEA-like protein 1

Related Diseases

Diseases Alias
Amelogenesis Imperfecta, Hypomaturation Type, Iia3

Amelogenesis Imperfecta Hypomaturation Type 2a3

AI2A3

Amelogenesis Imperfecta Hypomaturation Type Iia3

Amelogenesis Imperfecta, Type Iia3

Amelogenesis Imperfecta Type Iia3

Amelogenesis Imperfecta, Hypomaturation Type, 2a3
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14294 TCEAL1 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus TCEAL1 VGNC VGNC:66017
Canis familiaris TCEAL1 VGNC VGNC:49659
Bos taurus TCEAL1 VGNC VGNC:49978
Macaca mulatta TCEAL1 VGNC VGNC:78282
Mus musculus TCEAL1 MGD MGI:2385317
Rattus norvegicus TCEAL1 RGD RGD:1549724