ZRANB2 - zinc finger RANBP2-type containing 2 Gene

Also Known as ZIS; ZIS1; ZIS2; ZNF265

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 9406

About ZRANB2

Cytogenetic location: 1p31.1 Genomic coordinates (GRCh38): 1:71,063,291-71,081,035 (from NCBI)

This gene has 7 transcripts (splice variants) and 213 orthologues. Ubiquitous expression in endometrium (RPKM 47.3), lymph node (RPKM 37.7) and 25 other tissues.

Summary

Enables RNA binding activity. Predicted to be involved in RNA splicing and mRNA processing. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

ZRANB2 Products (2)

mRNA Protein Name
NM_005455.5 NP_005446.2 zinc finger Ran-binding domain-containing protein 2 isoform 2
NM_203350.3 NP_976225.1 zinc finger Ran-binding domain-containing protein 2 isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
16982639 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZRANB2 Protein Structure

zf-RanBP

zf-RanBP: Zn-finger in Ran binding protein and others (10 - 35)

zf-RanBP

zf-RanBP: Zn-finger in Ran binding protein and others (66 - 93)

  • 0
  • 100
  • 200
  • 300
  • 330 a.a.
Protein Preferred Names Protein Names

zinc finger Ran-binding domain-containing protein 2

  • zinc finger protein 265

ZRANB2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
ZRANB2 O95218 LRRK2 Homo sapiens Q5S007
Protein Array
29513927
Intra
ZRANB2 O95218 ARRB1 Homo sapiens P49407
Anti Tag CoIP
17620599
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Acute Dacryoadenitis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS16194 ZRANB2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus ZRANB2 VGNC VGNC:37372
Canis familiaris ZRANB2 VGNC VGNC:48848
Felis catus ZRANB2 VGNC VGNC:67380
Rattus norvegicus ZRANB2 RGD RGD:61854
Mus musculus ZRANB2 MGD MGI:1858211
Others ZRANB2 NCBI