2. Metabolic Enzyme/Protease Apoptosis
  3. MMP Apoptosis
  4. GPLGIAGQ

GPLGIAGQ, a MMP2-cleavable polypeptide, is used as a stimulus-sensitive linker in both liposomal and micellar nanocarriers for MMP2-triggered tumor targeting. GPLGIAGQ can be used to synthesis unique MMP2-targeted photosensitizer in photodynamic therapy (PDT).

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GPLGIAGQ

GPLGIAGQ Estructura química

No. CAS : 109053-09-0

Tamaño Precio Stock Cantidad
5 mg En stock
10 mg En stock
25 mg En stock
50 mg En stock
100 mg   Obtener un presupuesto  
200 mg   Obtener un presupuesto  

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Based on 1 Customer Validation

Other Forms of GPLGIAGQ:

GPLGIAGQ Related Antibodies

Top Publications Citing Use of Products

Ver todos los productos específicos de isoformas MMP:

Ver todas las isoformas
MMP-1 MMP-2 MMP-3 MMP-8 MMP-9 MMP-13 MMP-14 MMP-17 ADAM10 ADAM17 MMP-7 MMP-12 MMP-10 MMP ADAM8 MMP-19

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  • Referencias

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Descripciòn

GPLGIAGQ, a MMP2-cleavable polypeptide, is used as a stimulus-sensitive linker in both liposomal and micellar nanocarriers for MMP2-triggered tumor targeting. GPLGIAGQ can be used to synthesis unique MMP2-targeted photosensitizer in photodynamic therapy (PDT)[1][2][3].

IC50 & Target

MMP2[1].
In Vitro

GPLGIAGQ is used to trigger PEG deshielding of liposomal carriers, resulting in enhanced cellular internalization[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

GPLGIAGQ Related Antibodies
Peso molecular

711.81

Fòrmula

C31H53N9O10
No. CAS
Appearance

Solid

Color

White to off-white

Sequence

Gly-Pro-Leu-Gly-Ile-Ala-Gly-Gln
Sequence Shortening

GPLGIAGQ
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvente y solubilidad
In Vitro: 

DMSO : 100 mg/mL (140.49 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.4049 mL 7.0243 mL 14.0487 mL
5 mM 0.2810 mL 1.4049 mL 2.8097 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Calculadora de molaridad

  • Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Pureza y Documentación
Referencias

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.4049 mL 7.0243 mL 14.0487 mL 35.1217 mL
5 mM 0.2810 mL 1.4049 mL 2.8097 mL 7.0243 mL
10 mM 0.1405 mL 0.7024 mL 1.4049 mL 3.5122 mL
15 mM 0.0937 mL 0.4683 mL 0.9366 mL 2.3414 mL
20 mM 0.0702 mL 0.3512 mL 0.7024 mL 1.7561 mL
25 mM 0.0562 mL 0.2810 mL 0.5619 mL 1.4049 mL
30 mM 0.0468 mL 0.2341 mL 0.4683 mL 1.1707 mL
40 mM 0.0351 mL 0.1756 mL 0.3512 mL 0.8780 mL
50 mM 0.0281 mL 0.1405 mL 0.2810 mL 0.7024 mL
60 mM 0.0234 mL 0.1171 mL 0.2341 mL 0.5854 mL
80 mM 0.0176 mL 0.0878 mL 0.1756 mL 0.4390 mL
100 mM 0.0140 mL 0.0702 mL 0.1405 mL 0.3512 mL
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GPLGIAGQ Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GPLGIAGQ109053-09-0MMPApoptosisMatrix metalloproteinasesPDTphotosensitizerInhibitorinhibitorinhibit

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Nombre del producto:
GPLGIAGQ
Cat. No.:
HY-P2213
Cantidad:
MCE Japan Authorized Agent:

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