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Cat. No.: HY-172599

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GSK-3β probe-1

GSK-3β probe-1 (10c) is a GSK-3β probe (Ex = 341 nm, Em= 574nm, ɛ= 3.51 × 10⁴L/mol·cm⁻¹) and can be be used in the study of Alzheimer's disease.

For research use only. We do not sell to patients.

Formula: C₂₆H₃₀N₈O₆S₂
Molecular Weight:614.70

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

GSK-3β probe-1 Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

GSK-3β probe-1 (10c) is a GSK-3β probe (Ex = 341 nm, Em= 574nm, ɛ= 3.51 × 10⁴L/mol·cm⁻¹) and can be be used in the study of Alzheimer's disease^[1].

All GSK-3 Isoforms :

Chemical Information

Molecular Weight 614.70
Formula C₂₆H₃₀N₈O₆S₂
SMILES

O=C(NCCCCNC1=CC=C(S(N(C)C)(=O)=O)C2=NON=C12)C3=C(OC)N=C(C4=CC=NC(NC(C5CC5)=O)=C4)S3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Chen Y, et al. Discovery of fluorescent and theranostic probes for glycogen synthase kinase-3β in living cells and brain tissues: Detection and imaging in models of Alzheimer's disease. Eur J Med Chem. 2025 Jul 5;291:117639. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
Chemical Information
Purity & Documentation
References

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GSK-3β probe-1

All GSK-3 Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

GSK-3β probe-1 Related Classifications

HY-172599 Related Classifications