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Cat. No.: HY-116696

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GSK3-IN-11

GSK3-IN-11 is a Glycogen Synthase Kinase-3 (GSK-3) inhibitor with an IC₅₀ of 5010 nM.

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CAS No.: 681432-07-5
Formule: C₂₅H₂₀N₆O₃
Masse moléculaire:452.47

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

GSK3-IN-11 Chemical Structure

CAS No.: 681432-07-5

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
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Activité biologique

Description

GSK3-IN-11 is a Glycogen Synthase Kinase-3 (GSK-3) inhibitor with an IC₅₀ of 5010 nM^[1].

IC₅₀ & Target^[1]

GSK-3

5010 nM (IC₅₀)

Voir tous les produits spécifiques à Isoform GSK-3 :

In Vitro

GSK3-IN-11 (Compound 117) inhibits GSK-3 with an experimental IC₅₀ of 5010 nM (pIC₅₀ = 5.300)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 681432-07-5
Masse moléculaire 452.47
Formule C₂₅H₂₀N₆O₃
SMILES

N1=CC=C(N=C1NC2=CC=C3OCCOC3=C2)C=4C(=NN5N=CC=CC45)C6=CC=C(OC)C=C6
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Katritzky AR, et al. QSAR modeling of the inhibition of glycogen synthase kinase-3. Bioorg Med Chem. 2006 Jul 15;14(14):4987-5002. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
Références

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GSK3-IN-11

Voir tous les produits spécifiques à Isoform GSK-3

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

GSK3-IN-11 Related Classifications

HY-116696 Related Classifications