2. Membrane Transporter/Ion Channel
  3. HCN Channel
  4. HCN2-IN-2

HCN2-IN-2 (Compound 35), azaindazole derivative, is a selective HCN2 inhibitor with an IC50 of 145 nM. HCN2-IN-2 inhibits HCN2 channel activity blocks abnormal firing of peripheral nociceptive neurons. HCN2-IN-2 can be used for the research of pain.

For research use only. We do not sell to patients.

HCN2-IN-2

HCN2-IN-2 Chemical Structure

CAS No. : 3080808-99-4

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Description

HCN2-IN-2 (Compound 35), azaindazole derivative, is a selective HCN2 inhibitor with an IC50 of 145 nM. HCN2-IN-2 inhibits HCN2 channel activity blocks abnormal firing of peripheral nociceptive neurons. HCN2-IN-2 can be used for the research of pain[1].

Molecular Weight

472.96

Formula

C24H29ClN4O4
CAS No.
SMILES

O=C(CC(C)(C)C)NC1=NN(CCC(C)(C)O)C2=NC=C(C3=C(Cl)C=C4OCOC4=C3)C=C12
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Purity & Documentation
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HCN2-IN-2 Related Classifications

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Keywords:

HCN2-IN-23080808-99-4HCN ChannelHyperpolarization activated cyclic nucleotide gated channelsInhibitorinhibitorinhibit

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