HCN2-IN-2
HCN2-IN-2 (Compound 35), azaindazole derivative, is a selective HCN2 inhibitor with an IC50 of 145 nM. HCN2-IN-2 inhibits HCN2 channel activity blocks abnormal firing of peripheral nociceptive neurons. HCN2-IN-2 can be used for the research of pain.
For research use only. We do not sell to patients.
- CAS No.: 3080808-99-4
- Formula: C24H29ClN4O4
- Molecular Weight:472.96
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Chemical Information
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CAS No. 3080808-99-4
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Molecular Weight 472.96
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Formula C24H29ClN4O4
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SMILES
O=C(CC(C)(C)C)NC1=NN(CCC(C)(C)O)C2=NC=C(C3=C(Cl)C=C4OCOC4=C3)C=C12
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
HCN2-IN-2 Related Classifications
HY-186066 Related Classifications
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