1. MAPK/ERK Pathway
  2. MAP4K
  3. HPK1-IN-12

HPK1-IN-12 is potent inhibitor of HPK1. HPK1 is a serine/threonine protein kinase cloned from hematopoietic progenitor cells and belongs to the MAP4K family of mammalian Ste-20-related protein kinases. HPK1-IN-12 has the potential for the research of HPK1 related diseases (extracted from patent WO2021213317A1, compound 85) .

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HPK1-IN-12

HPK1-IN-12 화학구조

CAS No. : 2734168-51-3

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제품 설명

HPK1-IN-12 is potent inhibitor of HPK1. HPK1 is a serine/threonine protein kinase cloned from hematopoietic progenitor cells and belongs to the MAP4K family of mammalian Ste-20-related protein kinases. HPK1-IN-12 has the potential for the research of HPK1 related diseases (extracted from patent WO2021213317A1, compound 85) [1].

분자량

445.49

화학식

C25H24FN5O2

CAS No.
SMILES

FC1=C(C2=NC3=C(C=C2)NN=C3C4=CC(OCC5N6CCN(C5)C)=C6C=C4)C(OC)=CC=C1

선적

Room temperature in continental US; may vary elsewhere.

보관

Please store the product under the recommended conditions in the Certificate of Analysis.

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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상품명:
HPK1-IN-12
Cat. No.:
HY-145038
수량:
MCE Japan Authorized Agent: