HPK1-IN-41
HPK1-IN-41 (compound Z389) is a HPK1 inhibitor with an IC50 value of 0.21 μM. HPK1-IN-41 can be used for the research of preventing and/or treating diseases or conditions associated with HPK1 activity.
For research use only. We do not sell to patients.
- CAS No.: 2828455-23-6
- Formula: C28H33N5O2
- Molecular Weight:471.59
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All MAP4K Isoforms
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Biological Activity
Description
IC50 & Target
IC50: 0.21 μM (HPK1)[1].
Chemical Information
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CAS No. 2828455-23-6
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Molecular Weight 471.59
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Formula C28H33N5O2
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SMILES
CC1=CNC2=C1C=C(C3=CC(CCN(C(N4CC5OC(CC5)C4)=O)C6)=C6C([C@@H]7CCCN7)=C3)C=N2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)