ICI-63197 (Standard)
ICI-63197 (Standard) is the analytical standard of ICI-63197 (HY-103024). This product is intended for research and analytical applications. ICI-63197 is a phosphodiesterase 3 (PDE3) and PDE4 inhibitor with Ki values of 9 µM and 10 µM, respectively. ICI-63197 is selectivity against PDE1 and PDE2. ICI-63197 has antidepressant effects.
For research use only. We do not sell to patients.
- CAS No.: 27277-00-5
- Formula: C9H13N5O
- Molecular Weight:207.23
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 27277-00-5
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Molecular Weight 207.23
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Formula C9H13N5O
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SMILES
O=C1N(CCC)C2=NC(N)=NN2C=C1C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. M Hoey, et al. Identification and selective inhibition of four distinct soluble forms of cyclic nucleotide phosphodiesterase activity from kidney. Biochem Pharmacol. 1990 Jul 15;40(2):193-202. [Content Brief]
[2]. H Wachtel. Potential antidepressant activity of rolipram and other selective cyclic adenosine 3',5'-monophosphate phosphodiesterase inhibitors. Neuropharmacology. 1983 Mar;22(3):267-72. [Content Brief]
[3]. H Johnston, et al. Prejunctional beta-adrenoceptors in rabbit pulmonary artery and mouse atria: effect of alpha-adrenoceptor blockade and phosphodiesterase inhibition. Br J Pharmacol. 1986 Mar;87(3):553-62. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)