Dendroside D
Dendroside D is a sesquiterpenoid compound. Dendroside D binds to the RNA site of RNA-dependent RNA polymerase and the active site of SARS-CoV-2 main protease through hydrogen bonds, electrostatic interactions, and hydrophobic interactions, thereby blocking viral replication. Dendroside D stimulates the proliferation of mouse T and B lymphocytes, promotes T and B lymphocyte proliferation, and exhibits immunomodulatory activity. Dendroside D can be used for viral infection and immune-related research.
For research use only. We do not sell to patients.
- CAS No.: 503443-09-2
- Formula: C27H44O14
- Molecular Weight:592.64
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
Dendroside D (15 mg; 7 days) is a glycoside that yields aglycone 1a and glucose upon enzymatic hydrolysis with β-cellulase[2].
The sugar moiety of Dendroside D (0.04 M; 1 h) is D-glucose, as confirmed by GLC retention time matching authentic D-glucose[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 503443-09-2
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Molecular Weight 592.64
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Formula C27H44O14
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SMILES
C(O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)(=O)[C@@]2(C)[C@@]3([C@]2(CC[C@](CO[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)(O)[C@@]5([C@]3([C@H](C)CC5)[H])[H])[H])[H]
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Dendroside D Related Classifications
HY-N21759 Related Classifications
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Keywords
- Dendroside D
- 503443-09-2
- Endogenous Metabolite
- DNA/RNA Synthesis
- Lipinski's rule of five
- hyaluronidase inhibitor
- COVID-19
- SARS-CoV-2 main protease active site
- RNA-dependent RNA polymerase RNA site
- molecular docking model
- SARS-CoV-2
- sesquiterpene guaiane group compound
- mouse T and B lymphocyte proliferation
- HAase catalytic site
- Inhibitor
- inhibitor
- inhibit